Prevalence and Incidence Of Transfusion Transmitted Infections Amongst VNRBDs In Central India
Prevalence And Incidence Of Transfusion Transmitted Infections Amongst VNRBDs
Keywords:
hepatitis B; hepatitis C; HIV; Syphilis; seroprevalenceAbstract
Background: The aim of this study is to present the status of transfusion –transmitted infections among the apparently healthy donors so as to increase the awareness of complications of blood transfusion and make the clinicians more vigilant with regard to judicious use of blood. Methodology: A total of 15322 units of donor’s blood were screened from January 2008 to December 2010 at blood bank of C R Gardi Hospital and R D Gardi medical college. Results and Conclusion: The result of screening showed total seropositive samples for hepatitis B were 288 (1.88%), hepatitis C 52 (0.34%), human immunodeficiency virus 57 (HIV; 0.37% ) and Venereal Disease Research Laboratory Test 135 (VDRL; 0.88%) by using enzyme linked immunosorbent assay (ELISA ) methods, and rapid plasma regain (RPR) method for syphilis. [Jain R NJIRM 2015; 6(4): 82-85]
References
1. Brecher, M.E., Butch, S.H., Calhoun, A.R., Fiebig, E.W., Goodnough, L.T., Hahn, L., Ladd, D.J., Mckenna, L., Pasters, H.J., Pierce, S.R., Pisciotto, P., Rearden, A., South, S.F., Storry, J.R. (ed.) (2005) Technical manual of the American Association of Blood Banks (15th edn), 283-336.
2. Choudhury, N., Phadke, S. (2001) Transfusion transmitted diseases. Indian Journal of Pediatrics, 68, 951-958.
3. Mine, H., Emura, H., Miyamoto, M. (2003) High throughtout screening of 16 million serologically negative blood donors for hepatitis B virus, hepatitis C virus and HIV type-1 by NAT with specific and sensitive multiplex reagent in Japan. Journal of Virology Methods, 112, 145-151.
4. Chandrasekaran S, Palaniappan N, Krishnan V, Mohan G, Chandrasekaran N: Relative prevalence of hepatitis B viral markers and hepatitis C virus antibodies (anti HCV) in Madurai, South India. Indian Journal of Medical Sciences, 2000;547:270-273.
5. Ness PM: Bacterial and protozoal infections transmitted by transfusion. In : Principles of
Transfusion Medicine. EC Rossi , TL Simon , GS Moss, (Eds.), 1st Edn; Williams & Wilkins, Baltimore, 1991: pp.611-618.
6. Pomper GJ, Wu YY, Synder EL: Risk of transfusion – transmitted infections. Current Opinion in Haematology, 2003;106:412-418.
7. Jain, R., Jim Perkins, Susan T. Johnson, Choudhury, N et al.: A prospective study for prevalence and/or development of transfusiontransmitted infections in multiply transfused thalassemia major patients. Asian Journal of Transfusion Sciences. 2012; Vol. 6, Issue 2, 151-154.
8. Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ: The risk of transfusion-transmitted viral infections. The New England Journal of Medicine, 1996;334(26):1685-1690.
9. Sharma RR, Cheema R, Vajpayee M, Rao U, Kumar S, Marwaha N, Agnihotri SK: Prevalence of markers of transfusion transmissible diseases in voluntary and replacement blood donors. The National Medical Journalof India, 2004;171:19-21.
10. Islam MB. Blood transfusion services in Bangladesh. Asian J Transf Sci. 2009;3:108–110. doi: 10.4103/0973-6247.53880. [PMC free article] [PubMed] [Cross Ref]
11. Khan ZT, Asim S, Tariz Z, Ehsan IA, Malik RA, Ashfaq B, et al. Prevalence of Transfusion transmitted infections in healthy blood donors in Rawalpindi District, Pakistan–a five year study. Int J Pathol. 2007;5:21–25.
12. Arora D, Arora B, Khetarpal A. Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana. Indian J Pathol Microbiol. 2010;53:308–309. doi: 10.4103/0377-4929.64295. [PubMed] [Cross Ref]
13. Fiebig EW, Busch MP. Emerging infections in transfusion medicine. Clin Lab Med. 2004;24:797–823. doi: 10.1016/j.cll.2004.05.009. [PubMed] [Cross Ref]
14. Gupta PK, Kumar H, Basannar DR, Jaiprakash M. Transfusion transmitted in infections in armed forces: prevalence and trends. MJAFI. 2006;62: 348–350.
15. Rao P, Annapurna K. HIV status of blood donors and patients admitted in KEM hospital, Pune. Ind J Hemat Blood Transf. 1994;12:174–17
16. Singh K, Bhat S, Shastry S. Trend in seroprevalence of Hepatitis B virus infection among blood donors of coastal Karnataka, India. J Infect Dev Ctries. 2009;3:376–379. [PubMed].
17. Pahuja S, Sharma M, Baitha B, Jain M. Prevalence and trends of markers of hepatitis C virus, hepatitis B virus and humany immunodeficiency virus in Delhi blood donors. A hospital based study. Jpn J Inf Dis. 2007;60:389–391. [PubMed].
18. Bhattacharya P, Chakraborty S, Basu SK. Significant increase in HBV, HCV, HIV and syphilis infections among blood donors in West Bengal, Eastern India 2004–2005. Exploratory screening reveals high frequency of occult HBV infection. World J Gastroenterol. 2007;13:3730–3733. [PMC free article] [PubMed].
19. Srikrishna A, Sitalakshmi S, Damodar P. How safe are our safe donors. Indian J Pathol Microbiol. 1999;42:411–416. [PubMed].
20. Garg S, Mathur DR, Gard DK. Comparison of seropositivity of HIV, HBV, HCV and syphilis in replacement and voluntary blood donors in western India. Indian J Pathol Microbiol. 2001;44:409–412. [PubMed].
21. Gupta N, Kumar V, Kaur A. Seroprevalence of HIV, HBV, HCV and syphilis in voluntary blood donors. Indian J Med Sci. 2004;58:255–257. [PubMed].
2. Choudhury, N., Phadke, S. (2001) Transfusion transmitted diseases. Indian Journal of Pediatrics, 68, 951-958.
3. Mine, H., Emura, H., Miyamoto, M. (2003) High throughtout screening of 16 million serologically negative blood donors for hepatitis B virus, hepatitis C virus and HIV type-1 by NAT with specific and sensitive multiplex reagent in Japan. Journal of Virology Methods, 112, 145-151.
4. Chandrasekaran S, Palaniappan N, Krishnan V, Mohan G, Chandrasekaran N: Relative prevalence of hepatitis B viral markers and hepatitis C virus antibodies (anti HCV) in Madurai, South India. Indian Journal of Medical Sciences, 2000;547:270-273.
5. Ness PM: Bacterial and protozoal infections transmitted by transfusion. In : Principles of
Transfusion Medicine. EC Rossi , TL Simon , GS Moss, (Eds.), 1st Edn; Williams & Wilkins, Baltimore, 1991: pp.611-618.
6. Pomper GJ, Wu YY, Synder EL: Risk of transfusion – transmitted infections. Current Opinion in Haematology, 2003;106:412-418.
7. Jain, R., Jim Perkins, Susan T. Johnson, Choudhury, N et al.: A prospective study for prevalence and/or development of transfusiontransmitted infections in multiply transfused thalassemia major patients. Asian Journal of Transfusion Sciences. 2012; Vol. 6, Issue 2, 151-154.
8. Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ: The risk of transfusion-transmitted viral infections. The New England Journal of Medicine, 1996;334(26):1685-1690.
9. Sharma RR, Cheema R, Vajpayee M, Rao U, Kumar S, Marwaha N, Agnihotri SK: Prevalence of markers of transfusion transmissible diseases in voluntary and replacement blood donors. The National Medical Journalof India, 2004;171:19-21.
10. Islam MB. Blood transfusion services in Bangladesh. Asian J Transf Sci. 2009;3:108–110. doi: 10.4103/0973-6247.53880. [PMC free article] [PubMed] [Cross Ref]
11. Khan ZT, Asim S, Tariz Z, Ehsan IA, Malik RA, Ashfaq B, et al. Prevalence of Transfusion transmitted infections in healthy blood donors in Rawalpindi District, Pakistan–a five year study. Int J Pathol. 2007;5:21–25.
12. Arora D, Arora B, Khetarpal A. Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana. Indian J Pathol Microbiol. 2010;53:308–309. doi: 10.4103/0377-4929.64295. [PubMed] [Cross Ref]
13. Fiebig EW, Busch MP. Emerging infections in transfusion medicine. Clin Lab Med. 2004;24:797–823. doi: 10.1016/j.cll.2004.05.009. [PubMed] [Cross Ref]
14. Gupta PK, Kumar H, Basannar DR, Jaiprakash M. Transfusion transmitted in infections in armed forces: prevalence and trends. MJAFI. 2006;62: 348–350.
15. Rao P, Annapurna K. HIV status of blood donors and patients admitted in KEM hospital, Pune. Ind J Hemat Blood Transf. 1994;12:174–17
16. Singh K, Bhat S, Shastry S. Trend in seroprevalence of Hepatitis B virus infection among blood donors of coastal Karnataka, India. J Infect Dev Ctries. 2009;3:376–379. [PubMed].
17. Pahuja S, Sharma M, Baitha B, Jain M. Prevalence and trends of markers of hepatitis C virus, hepatitis B virus and humany immunodeficiency virus in Delhi blood donors. A hospital based study. Jpn J Inf Dis. 2007;60:389–391. [PubMed].
18. Bhattacharya P, Chakraborty S, Basu SK. Significant increase in HBV, HCV, HIV and syphilis infections among blood donors in West Bengal, Eastern India 2004–2005. Exploratory screening reveals high frequency of occult HBV infection. World J Gastroenterol. 2007;13:3730–3733. [PMC free article] [PubMed].
19. Srikrishna A, Sitalakshmi S, Damodar P. How safe are our safe donors. Indian J Pathol Microbiol. 1999;42:411–416. [PubMed].
20. Garg S, Mathur DR, Gard DK. Comparison of seropositivity of HIV, HBV, HCV and syphilis in replacement and voluntary blood donors in western India. Indian J Pathol Microbiol. 2001;44:409–412. [PubMed].
21. Gupta N, Kumar V, Kaur A. Seroprevalence of HIV, HBV, HCV and syphilis in voluntary blood donors. Indian J Med Sci. 2004;58:255–257. [PubMed].
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2018-01-11
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Jain, D. R., Jain, D. P., Mahadik, D. V. K., & Choudhury, D. N. (2018). Prevalence and Incidence Of Transfusion Transmitted Infections Amongst VNRBDs In Central India: Prevalence And Incidence Of Transfusion Transmitted Infections Amongst VNRBDs. National Journal of Integrated Research in Medicine, 6(4), 82–85. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/943
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