Periodontitis And Cardiovascular Disease - A Much Discussed Relationship
Periodontitis And Cardiovascular Disease
Keywords:
Periodontitis, Cardiovascular Disease, AtherosclerosisAbstract
Periodontitis and atherosclerosis have many potential pathogenic mechanisms in common. Both diseases have complex etiologies, genetic and gender predispositions, and potentially share many risk factors—the most significant of which may be smoking status. The objective of this review is to consider the mechanisms whereby diseases such as Periodontitis, which is chronic and inflammatory in nature and initiated by microbial plaque, can predispose to cardiac conditions.
References
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13. lowe GD, Lee AJ, Rumley A, et al:blood viscosity and risk of cardiovascular events: theedinburg artery study, Br J Haematol 96:168,1997.
14. lowe GD etiopathogenesis of cardiovascular disease:hemostasis, thrombosis and vascular medicine, Ann Periodontal 3:121,1998.
15. Ridker PM: Fibrinolytic and inflammatory markers for arterial occlusin: the evolving epidemiology of thrombosis and hemostasis, Thromb Haemost 78:53,1997
16. Herzberg MC, Meyer MW: Dental plaque, platelets and cardiovascular disease, Ann Periodontol 3:151,1998
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18. Ross RL: Atherosclerosis - an inflammatory disease, N Engl J Med 342:115,1999
19. Beck JD, Offenbacher S: The association between periodontal disease and cardiovascular disease: a state of-the-art review,Ann Periodontol 6:9,2001.
20. Kinane DF: Periodontal disease's contribution to cardiovascular disease: an overview of potential mechanisms, Ann Periodontol 3:142,1998
21. Mattila KJ, Nieminen MS, Valtonen VV, Rasi VP, Kesäniemi YA, Syrjälä SL, et al. Association between dental health and acute myocardial infarction. BMJ. 1989;298:779–82.
22. Joshipura KJ, Rimm EB, Douglass CW, Trichopoulos D, Ascherio A, Willett WC. Poor oral health and coronary heart disease. J Dent Res. 1996;75:1631–6.
23. Janket SJ, Baird AE, Chuang SK, Jones JA. Meta-analysis of periodontal disease and risk of coronary heart disease and stroke. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95:559–69.
24. DeStefano F, Anda RF, Kahn HS, Williamson DF, Russell CM. Dental disease and risk of coronary heart disease and mortality. BMJ. 1993;306:688–91
25. Lederman, D., Lumerman, H., Reuben, S. & Freedman, P. D. (1984). Gingival hyperplasia associated with nifedipine therapy. Report of a case. Oral Surgery, Oral Medicine and Oral Pathology 57, 620–622.
26. Nery, E. B., Edson, R. G., Lee, K. K., Pruthi, V. K. & Watson, J. (1995). Prevalence of nifedipine-
induced gingival hyperplasia. Journal of Periodontology 66, 572–578.
27. Ellis, J. S., Seymour, R. A., Monkman, S. C. & Idle, J. R. (1992). Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth. Lancet 339, 1382–1383.
28. Seymour, R. A., Ellis, J. S., Thomason, J. M., Monkman, S. & Idle, J. R. (1994). Amlodipine- induced gingival overgrowth. Journal of Clinical Periodontology 21, 281–283.
29. Turesky, S., Breuer, M. & Coffman, G. (1992). The effect of certain systemic medications on oral calculus formation. Journal of Periodontology 63, 871–875.
30. Breuer, M. M., Mboya, S. A., Moroi, H. & Turesky, S. S. (1996). Effect of selected betablockers on supragingival calculus formation. Journal of Periodontology 67, 428–432.
31. Beck J, Garcia R, Heiss G, Vokonas PS, Offenbacher S. Periodontal disease and cardiovascular disease. J Periodontol. 1996;67:1123–
32. Mattila KJ, Asikainen S, Wolf J, Jousimies-Somer H, Valtonen V, Nieminen M. Age, dental infections and coronary heart disease. J Dent Res
33. Ford ES, Giles WH, Myers GL, Mannino DM. Population distribution of high sensitivity C- Reactive protein among U.S Men: Finding from National Health and nutrition Examination survey 1999 – 2000.Clin Chem. 2003;49:686–90
34. Blaizot A, Vergnes JN, Nuwwareh S, Amar J, Sixou M. Periodontal diseases and cardiovascular events: Meta-analysis of observational studies. Int Dent J. 2009;59:197–209
35. European workshop in periodontal health and cardiovascular disease—scientific evidence on the association between periodontal and cardiovascular diseases: a review of the literature.
Programme. Geneva:World Health Organization; 2003.
2. James D. Beck* and steven offenbacher*the association between periodontal disease and cardiovascular diseases : a state of the science review.
3. Pussinen PJ, Paju S, Ma¨ntyla¨ P, Sorsa T. Serum microbial and host-derived markers of periodontal diseases: A review. Curr Med Chem 2007;14:2402-2412.
4. Hettne KM, Weeber M, Laine ML, et al. Automatic mining of the literature to generate new hypotheses for the possible link between periodontitis and atherosclerosis: Lipopolysaccharide as a case study. J Clin Periodontol 2007;34:1016-1024.
5. Lo¨sche W, Marshal GJ, Krause S, Kocher T, Kinane DF. Lipoprotein-associated phospholipase A2 and plasma lipids in patients with destructive periodontaldisease. J Clin Periodontol 2005;32:640-644.
6. Wendel M, Paul R, Heller AR. Lipoproteins in inflammation and sepsis. II. Clinical aspects. Intensive CareMed 2007;33:25-35.
7. Hettne KM, Weeber M, Laine ML, et al. Automatic mining of the literature to generate new hypotheses for the possible link between periodontitis and atherosclerosis: Lipopolysaccharide as a case study. J Clin Periodontol 2007;34:1016-1024.
8. Is there an association between periodontal disease and acute myocardial infarction?A cross-sectional study
9. Lloyd-Jones DM, Larson MG, Beiser A, Levy D. Life time risk of developing coronary heart disease.Lancet. 1999;353:89–92.
10. Strong JP. atherosclerotic lesions. Natural history, risk factors and topography Arch Pathol Lab Med 1992;116:1268-1275}
11. Blaizot A, Vergnes JN, Nuwwareh S, Amar J, Sixou M. Periodontal diseases and cardiovascular events: Meta-analysis of observational studies. Int Dent J. 2009;59:197–209.
12. Strong JP. atherosclerotic lesions. Natural history, risk factors and topography Arch Pathol Lab Med 1992;116:1268-1275.
13. lowe GD, Lee AJ, Rumley A, et al:blood viscosity and risk of cardiovascular events: theedinburg artery study, Br J Haematol 96:168,1997.
14. lowe GD etiopathogenesis of cardiovascular disease:hemostasis, thrombosis and vascular medicine, Ann Periodontal 3:121,1998.
15. Ridker PM: Fibrinolytic and inflammatory markers for arterial occlusin: the evolving epidemiology of thrombosis and hemostasis, Thromb Haemost 78:53,1997
16. Herzberg MC, Meyer MW: Dental plaque, platelets and cardiovascular disease, Ann Periodontol 3:151,1998
17. Herzberg MC, Meyer MW:Effects of oral flora on platelets: Possible consequences on cardiovascular disease, J Periodontol 67:1138, 1996
18. Ross RL: Atherosclerosis - an inflammatory disease, N Engl J Med 342:115,1999
19. Beck JD, Offenbacher S: The association between periodontal disease and cardiovascular disease: a state of-the-art review,Ann Periodontol 6:9,2001.
20. Kinane DF: Periodontal disease's contribution to cardiovascular disease: an overview of potential mechanisms, Ann Periodontol 3:142,1998
21. Mattila KJ, Nieminen MS, Valtonen VV, Rasi VP, Kesäniemi YA, Syrjälä SL, et al. Association between dental health and acute myocardial infarction. BMJ. 1989;298:779–82.
22. Joshipura KJ, Rimm EB, Douglass CW, Trichopoulos D, Ascherio A, Willett WC. Poor oral health and coronary heart disease. J Dent Res. 1996;75:1631–6.
23. Janket SJ, Baird AE, Chuang SK, Jones JA. Meta-analysis of periodontal disease and risk of coronary heart disease and stroke. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95:559–69.
24. DeStefano F, Anda RF, Kahn HS, Williamson DF, Russell CM. Dental disease and risk of coronary heart disease and mortality. BMJ. 1993;306:688–91
25. Lederman, D., Lumerman, H., Reuben, S. & Freedman, P. D. (1984). Gingival hyperplasia associated with nifedipine therapy. Report of a case. Oral Surgery, Oral Medicine and Oral Pathology 57, 620–622.
26. Nery, E. B., Edson, R. G., Lee, K. K., Pruthi, V. K. & Watson, J. (1995). Prevalence of nifedipine-
induced gingival hyperplasia. Journal of Periodontology 66, 572–578.
27. Ellis, J. S., Seymour, R. A., Monkman, S. C. & Idle, J. R. (1992). Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth. Lancet 339, 1382–1383.
28. Seymour, R. A., Ellis, J. S., Thomason, J. M., Monkman, S. & Idle, J. R. (1994). Amlodipine- induced gingival overgrowth. Journal of Clinical Periodontology 21, 281–283.
29. Turesky, S., Breuer, M. & Coffman, G. (1992). The effect of certain systemic medications on oral calculus formation. Journal of Periodontology 63, 871–875.
30. Breuer, M. M., Mboya, S. A., Moroi, H. & Turesky, S. S. (1996). Effect of selected betablockers on supragingival calculus formation. Journal of Periodontology 67, 428–432.
31. Beck J, Garcia R, Heiss G, Vokonas PS, Offenbacher S. Periodontal disease and cardiovascular disease. J Periodontol. 1996;67:1123–
32. Mattila KJ, Asikainen S, Wolf J, Jousimies-Somer H, Valtonen V, Nieminen M. Age, dental infections and coronary heart disease. J Dent Res
33. Ford ES, Giles WH, Myers GL, Mannino DM. Population distribution of high sensitivity C- Reactive protein among U.S Men: Finding from National Health and nutrition Examination survey 1999 – 2000.Clin Chem. 2003;49:686–90
34. Blaizot A, Vergnes JN, Nuwwareh S, Amar J, Sixou M. Periodontal diseases and cardiovascular events: Meta-analysis of observational studies. Int Dent J. 2009;59:197–209
35. European workshop in periodontal health and cardiovascular disease—scientific evidence on the association between periodontal and cardiovascular diseases: a review of the literature.
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Published
2014-02-28
How to Cite
v Toliya, D. A., Patel, D. V., Panchal, D. A., Mehta, D. H., & Nanavati, D. B. (2014). Periodontitis And Cardiovascular Disease - A Much Discussed Relationship: Periodontitis And Cardiovascular Disease. National Journal of Integrated Research in Medicine, 5(1), 103–107. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/687
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