National Journal of Integrated Research in Medicine

A prospective and comparative study to evaluate the efficacy of Dermaroller and Minoxidil combination treatment in androgenic alopecia

2025-03-27T19:24:57+00:00

Background:Minoxidil has better efficacy when combined with dermaroller. Dermaroller
stimulates proliferation and differentiation of stem cells in the hair follicles bulge are a via multiple
molecular mechanisms. Methods: They have emerged as new non-surgical treatment modalities for AGA,
with minimal side effects and good safety profile. It is a promising treatment option in patients who cannot
afford hair transplantation. Results: Our study showed best results in patients treated with Derma roller
and minoxidil. Conclusion: It is a promising therapeutic modality with an excellent safety profile and patient
satisfaction. [Shah R Natl J Integr Res Med, 2024; 16(1): 01-03, Published on Dated: 26/02/2025]

Translation and Cross Cultural Adaptation of Health Literacy Instrument For Adults in Hindi.

2025-03-27T19:30:16+00:00

Physiotherapists play a significant role in health promotion and wellness. Health literacy can help people prevent health problems, protect health and better manage diseases when they arise.There are lack of tool available to measure health literacy in Indian language and according to Indian culture. Aim of the study was to translate and cross culturally adapt Health literacy instrument for adults (HELIA) and determine the reliability and validity.Method: Methodological study was done on adults aged 18-65 years where permission to translate the scale was taken from the author. The health literacy instrument for adults was translated into Hindi using forward-backward translation method given by WHO. Forward translation of the scale was done by a Hindi professor such as to preserve meaning of the questions in original questionnaire. There was expert panel of five experts (2 physiotherapists, 2 doctors, 1 engineer). Following their suggestions, validated Hindi version 1 was made. Backward translation was done by an independent translator. Version 1 of Hindi version was pilot tested with 10 adults whose mean age was(42.3 ± 9.75) years. Suggestions given by them were done and final version 2 was given to 20 participants for reliability. One therapist performed scale twice on the same participants for intra-rater reliability and two therapists performed it on same participants for inter-rater reliability, both with two days of gap. Correlation and content validity was found. Data was analysed using SPSS 20.Results: There is strong positive correlation between English and Hindi version of HELIA with intraclass correlation (ICC=0.89) and interclass correlation (ICC=0.84). Scale content validity index (SCVI) is 0.91 .Conclusion: Hindi version of HELIA is reliable and valid for assessing health literacy in adults. That can be used for assessing health literacy in Hindi speaking community dwelling Indian adults. Clinical management and research may benefit from the availability of a self-administered scale in native language. [Jain A Natl J Integr Res Med, 2024; 15(1): 04-07, Published on Dated: 26/01/2025]

Association between Benign Paroxysmal Positional Vertigo and Balance: A Narrative Review

2025-03-27T19:40:26+00:00

Benign Paroxysmal Positional Vertigo (BPPV) is characterized by brief episodes of vertigo, nausea and/or positional nystagmus upon head movements, is produced by the inadequate presence of statocone particles coming from the utriculus macula floating in the endolymph of the semi-circular canal or attached to their cupule. BPPV is one of the most common peripheral vestibular disorders leading to balance difficulties and increased fall risks. Most patients complain of a loss of equilibrium and unstable gait during and between the vertigo attacks. Literature was explored on search engines (Google scholar, scihub and PubMed) and databases for articles published from 2014 to 2022. The key search phrase, balance and Benign Paroxysmal Positional Vertigo were used to identify potentially relevant articles. The following inclusion criteria were applied for article selection: (1) studies exploring balance in subjects with BPPV. (2) Studies that rated at a score of 7 or higher according to the Pedro scale. Many n=53 relevant articles were identified. After reading the titles and abstracts and assessing eligibility based on the full-text articles, 27 publications were included in our review. Majority studies showed that the outcome (ADL functions, Postural stability, nystagmus, balance, falls, and signs of consciousness) for BPPV reviewed were significantly associated with equilibrium. It was interpreted that balance was significantly affected in patients of BPPV. Also there was still imbalance in long-term even after successful treatment with repositioning maneuvers.

A Prospective Study To Evaluate The Efficacy Of Platelet-Rich Plasma With Microneedling In Androgenetic Alopecia

2025-03-27T19:52:26+00:00

Background: Platelet-Rich Plasma(PRP) has better efficacy when combined with dermaroller.
Dermaroller stimulates proliferation and differentiation of stem cells in the hair follicles bulge are a via
multiple molecular mechanisms. Methods: Platelet-rich plasma (PRP) is a simple and safe procedure, which has
been used for soft tissue and wound healing. PRP has been used in dermatology for skin rejuvenation and alopecia.
They have emerged as new non-surgical treatment modalities for AGA, with minimal side effects and
good safety profile. It is a promising treatment option in patients who cannot afford hair
transplantation. Results: Total 90 patients included in this study, 15 were female and 75 were male
patients. Their age varied from 22 to 48 years with a median age of 32 years. According to subjective scores
(PSS), eight patients had excellent results, forty two had very good, 26 had good, 8 had fair results, and 6
(10%) did not have any response. Objective assessment scores (OAS) showed that eight patients had
excellent results, 42 had very good, 26 had good, 8 had fair results, and 6 did not have any response.
Conclusion: The effect of microneddling by dermaroller with PRP has shown a considerable increase in hair
counts in the majority of the subjects in present study. Present study showed excellent results in patients
treated with Plapelet-Rich Plasma and Dermaroller. It is really a promising therapeutic modality with
an excellent safety profile and patient satisfaction.[Shah R, Natl J Integr Res Med, 2025; 16(1):14-18,
Published on Dated: 26/02/2025]