Hyaluronon As An Adjunct To Coronally Advanced Flap For The Treatment Of Gingival Recession Defects
Hyaluronon As An Adjunct To Coronally Advanced Flap For The Treatment Of Gingival Recession Defects
Keywords:
Gingival recession, Root coverage, Hyaluronic acid, RegenerationAbstract
Background: The present clinical trial was undertaken to evaluate the effectiveness of hyaluronon(HA) as an adjunct in root coverage procedures. Methodology: 20 patients with millers class I and II gingival recession in a minimum of two sites were treated with HA gel combined with coronally advanced flap on the test site and sub epithelial connective tissue graft with CAF on the control sites. Results: The percentage of root coverage achieved showed no significant difference between the test and control sites at 9 months post therapy. Conclusion: HA increased the probability of achieving root coverage in Miller’s class I and II recession. [Rajan P NJIRM 2015; 6(2):94-100]
References
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9. Robert P. Rubins, Paul N. Tolmie, Kenneth T. Corsig, Eric N. Kerr, David M. Kim.Subepithelial Connective Tissue Graft with Growth Factor for the Treatment of Maxillary Gingival Recession Defect. Int J Periodontics Restorative Dent 2013;33:43–9.
10. Huang LH, Neiva RE, Soehren SE, Giannobile WV, Wang HL. The effect of platelet-rich plasma on the coronally advanced flap root coverage procedure: A pilot human trial. J Periodontol 2005 Oct;76(10):1768-77. 11. Padma R, Shilpa A, Kumar PA, Nagasri M, Kumar C, Sreedhar A. A split mouth randomized controlled study to evaluate the adjunctive effect of platelet-rich fibrin to
coronally advanced flap in Miller's class-I and II recession defects. J Indian Soc Periodontol 2013; 17(5): 631–6.
12. Laurent TC, Fraser JR. Hyaluronan. FASEB J. 1992;6(7):2397-404.
13. Weigel,P.H.,Frost SJ,McGaryCT and Leboeuf RD. The role of hyaluronic acid in inflammation and wound healing. Int J Tiss Reac 1988;10:355-65. 14. Mazzione A, Baiguera R, Rossini S, et al. Pharmacological effect of hyaluronic acid (HA) on phagocytes: Hypothesis for an HA-induced monocyte chemotatic factor for neutrophils. Clinical Therapeutics 1986; 8(5): 527-36.
15. Moseley R, Waddington RJ, Embery G. Hyaluronan and its potential role in periodontal healing. Dent Update.2002;29(3):144-8.
16. Pirnazar P, Wolinsky L, Nachnani S, Haake S, Pilloni A, Bernard GW. Bacteriostatic effects of hyaluronic acid. J Periodontol. 1999;70(4):370-4.
17. Sakasi T, Watanabe C. Stimulation of osteoinduction in bone wound healing by high-molecular hyaluronic acid.Bone.1995 ;16(1):9-15. 18. Allen EP, Miller PD. Coronal positioning of existing gingiva: Short term results in the treatment of shallow marginal tissue recession. J Periodontol 1989; 60:316-9. 19. Edel A. Clinical evaluation of free connective tissue grafts used to increase the width of keratinized gingiva. J Clin Periodontol 1974;1(4):185-96.
20. Eick S, Renatus A, Heinicke M, Pfister W, Stratul SI, Jentsch H. Hyaluronic Acid as an adjunct after scaling and root planing: A prospective randomized clinical trial. J Periodontol 2013;84(7):941-9. 21. Johannsen A, Tellefsen M, Wikesjo Ulf, Johannsen G. Local delivery of hyaluronan as an adjunct to scaling and root planing in the treatment of chronic periodontitis. J Periodontol. 2009;80:1493–7. 22. King SR, Hickerson WL, Proctor KG. Beneficial actions of exogenous hyaluronic acid on wound healing. Surgery 1991;109:76–84.
23. Vanden Boraegade L. Treatment of intrabony periodontal defects with esterified hyaluronic acid: Clinical report of 19 consecutive lesions.Int J Periodontics Restorative Dent 2009;29:315-23.
24. Francesco Briguglio, Enrico Briguglio, Roberto Briguglio, Carlo Cafiero.Treatment of infrabony periodontal defects using a resorbable biopolymer of hyaluronic acid: A randomized clinical trial. Quintessence Int 2013;44:231–40. 25. Pini Prato GP, Baldi C, Nieri M, Franseschi D, Cortellini P, Clauser C. Coronally advanced flap: The post surgical position of the gingival margin is an important factor for achieving complete root coverage. J Periodontol2005;76:713–22.
26. Ulf M. E. Wikesjo and Knut A Selvig. Periodontal wound healing and regeneration.Periodontol 2000 1999;19(1): 21–39.
27. M Calvin. Cutaneous wound repair. Wounds: A Compendium of Clinical Research and Practice 1998;10(1):12-32.
28. Rosetti EP, Marcantonio RA, Rossa C Jr, Chaves ES, Goissis G, Marcantonio E Jr. Treatment of gingival recession: Comparative study between subepithelial connective tissue graft and guided tissue regeneration. J Periodontol 2000;71:1441
2. Thomson WM,Hashim R,Pack AR. The prevalence and intraoral distribution of periodontal attachment loss in a birth cohort of 26-years-olds. J Periodontol 2000 ;71:1840-5.
3. Rees JS, Addy M. A cross sectional study of dentine hypersensitivity. J clin Periodontal 2002; 29: 997- 1003.
4. Goutoudi P, Koidis PT, Konstantindis A. Gingival recession; A cross sectional clinical investigation. Eur J Prosthodont Restor Dent 1997;5:57 -61.
5. Roccuzzo M, Bunino M, Needleman I, Sanz M. Periodontal plastic surgery for treatment of localized gingival recession: A systemic review. J Clin Periodontal 2002; 29 suppl ( 3): 178-94.
6. Oatez TW, Robinson M, Gunsolley JC. Surgical therapies for the treatment of gingival recession. A systematic review. Ann periodontal 2003; 8 (1): 303-20.
7. Chambrone L,Sukekava F,Araujo MG,Pustiglioni FE, Chambrone LA,Lima LA.Root coverage procedures for the treatment of localised recession type defects: A Cochrane systematic review. J Periodontol 2010;81:452-78.
8. Abbas F, Wennstrom J.Vander Weijden F,Schneider T,Van der Velden U.surgical treatment of gingival recessions using emdogain gel: clinical procedures and case reports. Int J Periodontics Restorative Dent 2003;23:607-13.
9. Robert P. Rubins, Paul N. Tolmie, Kenneth T. Corsig, Eric N. Kerr, David M. Kim.Subepithelial Connective Tissue Graft with Growth Factor for the Treatment of Maxillary Gingival Recession Defect. Int J Periodontics Restorative Dent 2013;33:43–9.
10. Huang LH, Neiva RE, Soehren SE, Giannobile WV, Wang HL. The effect of platelet-rich plasma on the coronally advanced flap root coverage procedure: A pilot human trial. J Periodontol 2005 Oct;76(10):1768-77. 11. Padma R, Shilpa A, Kumar PA, Nagasri M, Kumar C, Sreedhar A. A split mouth randomized controlled study to evaluate the adjunctive effect of platelet-rich fibrin to
coronally advanced flap in Miller's class-I and II recession defects. J Indian Soc Periodontol 2013; 17(5): 631–6.
12. Laurent TC, Fraser JR. Hyaluronan. FASEB J. 1992;6(7):2397-404.
13. Weigel,P.H.,Frost SJ,McGaryCT and Leboeuf RD. The role of hyaluronic acid in inflammation and wound healing. Int J Tiss Reac 1988;10:355-65. 14. Mazzione A, Baiguera R, Rossini S, et al. Pharmacological effect of hyaluronic acid (HA) on phagocytes: Hypothesis for an HA-induced monocyte chemotatic factor for neutrophils. Clinical Therapeutics 1986; 8(5): 527-36.
15. Moseley R, Waddington RJ, Embery G. Hyaluronan and its potential role in periodontal healing. Dent Update.2002;29(3):144-8.
16. Pirnazar P, Wolinsky L, Nachnani S, Haake S, Pilloni A, Bernard GW. Bacteriostatic effects of hyaluronic acid. J Periodontol. 1999;70(4):370-4.
17. Sakasi T, Watanabe C. Stimulation of osteoinduction in bone wound healing by high-molecular hyaluronic acid.Bone.1995 ;16(1):9-15. 18. Allen EP, Miller PD. Coronal positioning of existing gingiva: Short term results in the treatment of shallow marginal tissue recession. J Periodontol 1989; 60:316-9. 19. Edel A. Clinical evaluation of free connective tissue grafts used to increase the width of keratinized gingiva. J Clin Periodontol 1974;1(4):185-96.
20. Eick S, Renatus A, Heinicke M, Pfister W, Stratul SI, Jentsch H. Hyaluronic Acid as an adjunct after scaling and root planing: A prospective randomized clinical trial. J Periodontol 2013;84(7):941-9. 21. Johannsen A, Tellefsen M, Wikesjo Ulf, Johannsen G. Local delivery of hyaluronan as an adjunct to scaling and root planing in the treatment of chronic periodontitis. J Periodontol. 2009;80:1493–7. 22. King SR, Hickerson WL, Proctor KG. Beneficial actions of exogenous hyaluronic acid on wound healing. Surgery 1991;109:76–84.
23. Vanden Boraegade L. Treatment of intrabony periodontal defects with esterified hyaluronic acid: Clinical report of 19 consecutive lesions.Int J Periodontics Restorative Dent 2009;29:315-23.
24. Francesco Briguglio, Enrico Briguglio, Roberto Briguglio, Carlo Cafiero.Treatment of infrabony periodontal defects using a resorbable biopolymer of hyaluronic acid: A randomized clinical trial. Quintessence Int 2013;44:231–40. 25. Pini Prato GP, Baldi C, Nieri M, Franseschi D, Cortellini P, Clauser C. Coronally advanced flap: The post surgical position of the gingival margin is an important factor for achieving complete root coverage. J Periodontol2005;76:713–22.
26. Ulf M. E. Wikesjo and Knut A Selvig. Periodontal wound healing and regeneration.Periodontol 2000 1999;19(1): 21–39.
27. M Calvin. Cutaneous wound repair. Wounds: A Compendium of Clinical Research and Practice 1998;10(1):12-32.
28. Rosetti EP, Marcantonio RA, Rossa C Jr, Chaves ES, Goissis G, Marcantonio E Jr. Treatment of gingival recession: Comparative study between subepithelial connective tissue graft and guided tissue regeneration. J Periodontol 2000;71:1441
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Published
2018-01-09
How to Cite
Rajan, P., Rao, N. M., Nera, M., & Rahaman, S. M. (2018). Hyaluronon As An Adjunct To Coronally Advanced Flap For The Treatment Of Gingival Recession Defects: Hyaluronon As An Adjunct To Coronally Advanced Flap For The Treatment Of Gingival Recession Defects. National Journal of Integrated Research in Medicine, 6(2), 95–101. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/891
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