Prevalence of Carbapenem Resistant Enterobacteriaceae in Various Clinical Specimen In A Tertiary Care Hospital, Ahmadabad
Prevalence of Carbapenem Resistant Enterobacteriaceae in Various Clinical Specimen
Keywords:
Carbapenemase, Enterobacteriaceae, Modified Hodge TestAbstract
Background and objectives: A study to find out prevalence of carbapenem resistant enterobacteriaceae among various clinical specimen received at Bacteriology Laboratory, Civil hospital, Ahmedabad. Methods: The study was conducted over a period of 5 month from June 2016 to October 2016. Total 16786 samples received. Enterobacteriaceae were isolated by standard microbiological identification techniques. The isolates were subjected to antimicrobial susceptibility testing by Modified Kirby bauer Disc Diffusion method. Imipenem resistant organisms were tested for carbapenemase production by Modified Hodge Test and double disk synergy test. Results: Among 16786 samples tested, 3276 belongs to enterobacteriaceae group. In which 357 screened for imipenem resistance. Carbapenemase production was identified in 268 (8.18%) isolates. Interpretation and Conclusion: This study provides prevalence of carbapenemase production among enterobacteriaceae, which shows rise in resistance against carbapenems. Hence there is a need of awareness among clinicians about the same as limited therapeutic options are available and they should be well versed with the strategies to manage multi drug resistant organism like carbapenem resistant enterobacteriaceae. judicious use of antibiotics and strict infectious control practices needs to be followed. [Khushbu V NJIRM 2017; 8(2):80-83]
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