Study on Weak D Prevalence among Blood Donors and Patients
A Study On Weak D Prevalence Among Blood Donors And Patients
Keywords:
Coomb’s gel card,Donor,Patient,Weak D antigenAbstract
Background and Objectives: Our study is designed to determine the frequency of weak D antigen in donors and patients coming to our tertiary care hospital which is important when labelling the donor and patient as the donor is labelled D positive, patient as D negative. Methodology: In our centre all blood donors and patients samples are tested for ABO and RhD using anti-D IgM monoclonal and a blend anti-D IgM and IgG reagents. The blood samples which were negative for agglutination by immediate spin method were further tested for weak D using IgG anti-D in the IAT phase with LISS/Coomb’s gel card. Results: A total 26020 blood samples were tested(4491 donors, 21529 patients) during the period September 2015 to September 2016.Among these 24489 were Rh D positive(94.11%) and remaining 1531(5.89%) were Rh D negative. A total of 05 were weakD positive constituting 0.326% of Rh D negative and 0.019 % of total individual screened. Conclusion: This study shows the prevalence of weakD antigen in our population and to inform them about their status as donor and recipient of blood to prevent the hazards of blood transfusion. [Moxda P NJIRM 2017; 8(2):35-38]
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