Clinico-Histopathological Analysis In Patients With Abnormal Uterine Bleeding
Clinico-Histopathological Analysis In Patients With Abnormal Uterine Bleeding
Keywords:
Abnormal Uterine Bleeding, Histological Findings, Clinical findingsAbstract
Background: Menstrual disturbance is one of the commonest gynecological problems for the curettage or hysterectomy specimen received by pathologist. During reproductive age group, approximately 9-30% of women suffer from menorrhagia or abnormal uterine bleeding & the incidence increases as age advances. Being most common gynecological problem, present study is aimed to know full spectrum of AUB and its pathological aspects. Methods: 200 cases were taken from NHL Municipal Medical College, Ahmedabad over a period of 3 years. Clinical history and radiological findings of cases of abnormal uterine bleeding were noted. Histopathological analysis was done. Data were analyzed and correlation between clinical and histopathological findings were studied. Results: Maximum numbers of patients were in 41-50 years (41.5%) of age group and next are in 31-40 years (38%) of age group. Proliferative pattern (24%) was most common pattern in non-structural causes of AUB and Leiomyoma (22.5%) was the most common structural cause of AUB. Pregnancy related causes of AUB were common in less than 40 years of age group. Malignancy was more common in more than 50 years of age group. Atrophic endometrium (33.33%) was the most common cause of post-menopausal bleeding. Conclusion: Endometrial specimen examination by histopathological evaluation is gold standard procedure to know the exact pathology for AUB and for further management of patients.[Falguni S NJIRM 2016; 7(5):14-17]
References
2. Divya Makhija, Alka Mary Mathai, Ramdos Naik, Suneet Kumar, Sharda Rai, Mukhta P Rai, Poornima Baliga. Morphometric evalution of endometrial blood vessels. Indian Journal of Pathology and Microbiology. 2008; 51 (31);346-350.
3. Elizabeth Farrell. Dysfunctional Uterine Bleeding. Australian Family Physical. 2004: 33(11): 906-908.
4. Arthur C. Guyton, John E. Hall Text Book of Medical Physiology. Philadelphia: Elsevier Saunders; 2006. 11th ed.
5. Moh. Aseel Ghazi Rifat. Endometrial Histopathological Changes in Women with Abnormal Uterine Bleeding in Kirkuk City, a Clinicalpathology Study. Medical Journal of Babylon-Vol. 10-No. 3-2013
6. Arti R. Anvikar, Nayan A. Ramteerthakar, Kalpana R. Sulhyan. Abnormal Uterine Bleeding - A Clinicopathological Study Of 160 Cases. Asian J Med Res. 2013;2(1):15-18
7. Doraiswami Saraswathi, Johnson Thanka, Rao Shalinee, Rajkumar Aarthi, Vijayaraghavan Jaya, Panicker Vinod Kumar. Study of Endometrial Pathology in Abnormal Uterine Bleeding. The Journal of Obstetrics and Gynecology of India (July-August 2011) 61 (4):426-430.
8. Fozia Umber Qureshi, Ahmed Wasim Yusuf. Distribution of causes of abnormal uterine bleeding using the new FIGO classification system. J Pak Med Assoc.2013;63(8):973-975
9. Jignasha Parmar, Deepak Desai. Study of endometrial pathology in abnormal uterine bleeding. Int J Reprod Contracept Obstet Gynecol. 2013;2(2):182-185.
10. Teri A. Longacre et al. in The Uterine Corpus, Sternberg’s Diagnostic Surgical Pathology 5th Ed.Lippincott Williams & Wilkins 2010 vol.2:2184-2277
