Prevalence of Candidemia in A Tertiary Care Hospital, Ahmedabad
Prevalence of Candidemia in a Tertiary Care Hospital, Ahmedabad
DOI:
https://doi.org/10.70284/njirm.v8i2.1223Keywords:
Antifungal Susceptibility, Blood Culture, CandidemiaAbstract
Background and Objectives: Candida species are the most common cause of fungal infections responsible for superficial, mucocutaneous, and invasive infections. To find out the prevalence of candidemia and antifungal susceptibility pattern of Candida isolates and various risk factors. Materials and Methods: All Candida isolates from blood culture were included in the six months study period from April to September-2016. The isolates were identified by using various phenotypic tests like germ tube test, corn meal agar, carbohydrates assimilation and fermentation tests. The species were also confirmed on chrome agar. Antifungal susceptibility testing was done by disc diffusion methods according to current Clinical and Laboratory Standard Institute (CLSI) guidelines. Results: Out of 3686 Blood Samples, 2048(55.56%) were culture positive. 129(6.29%) of the isolates were Candida species. Most common species identified was Candida parapsilosis. Most isolates were sensitive to Amphotericin B. 21.89% of isolates from blood were azole resistant. Conclusion: Candidemia is emerging as a significant problem in hospitalized patients, especially in ICU setups. Non-albicans Candida species are the major cause of candidemia as found in our study. Multicentric studies are required to know the true prevalence of candidemia and the status of antifungal drug resistance among Candida isolates. [Mistry U NJIRM 2017; 8(2):143-145]
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