National Journal of Integrated Research in Medicine

Role of individualized homeopathic Medicine in the Management of Endometritis: A Case Report of Successful Treatment with Pulsatilla

2026-10-02T11:01:23+00:00

Background: Endometritis is an inflammatory condition of the endometrial lining, commonly
caused by ascending infections of the genital tract. Despite standard antibiotic therapy, chronic and recurrent
cases remain a therapeutic challenge. Objective: To explore the role of individualized homeopathic medicine
in the management of chronic endometritis through a documented case. Case Presentation: A 30-year-old
female presented with chronic leucorrhoea, irregular menstruation, and pelvic discomfort for six months.
She had a history of recurrent antibiotic use with only temporary relief. Based on individualized symptom
totality—including emotional disposition, thermal modalities, and general characteristics—Pulsatilla was
prescribed. Results: Progressive improvement was observed over a period of three months, with complete
resolution of symptoms and no recurrence during six months of follow-up. Conclusion: Individualized
homeopathic treatment may offer a supportive therapeutic option in chronic endometritis, particularly in
cases with recurrent symptoms. Further controlled studies are recommended to validate these findings.
[Modi B Natl J Integr Res Med, 2026; 17(1): 37-40, Published on Dated: 07/07/2026]

Oral Tuberculosis In Disguise : Diagnostic Dilemma Of Gingival Enlargement

2026-10-07T05:37:40+00:00

Background: Tuberculosis (TB) is a chronic specific granulomatous disease and a major cause of death in developing countries. The clinical presentation of TB lesions of the oral cavity varies widely and can manifest as ulcerations, diffuse inflammatory lesions, granulomas and fissures. We hereby report a case of primary TB of the gingiva manifesting as gingival enlargement. Diagnosis was based on histopathological examination, complete blood count, X-ray chest and Ultra sonography of neck, and Sputum AFB test. Anti-tuberculous therapy was carried out for over 6 months. This case report emphasizes the need for dentists to include TB in the differential diagnosis of various types of gingival enlargements.[Patel V Natl J Integr Res Med, 2026; 17(1): 41-44, Published on Dated: 07/07/2026]

Glandular Odontogenic Cyst: A Rare Histopathological Entity with An Unpredictable Recurrence Pattern

2026-10-07T05:24:35+00:00

Background: Glandular odontogenic cyst (GOC) is a rare developmental odontogenic cyst
characterized by distinctive yet diagnostically challenging histopathological features and a recognized
propensity for recurrence. Histopathological examination in the present case revealed non-keratinized
hyperplastic epithelium with extensive mucous goblet cells, hobnail cells, and mucin-filled duct-like
structures, with Alcian blue confirming the mucinous component. Although these features supported the
diagnosis, the literature emphasizes that individual histological characteristics do not reliably predict
recurrence. The lesion’s potential for persistent and late recurrence underscores the importance of adequate
treatment and prolonged clinical and radiographic follow-up. Material and Methods: For the given specimen
H & E and alcian blue stain s were used. Result: Mucous cells were identified by using alcian blue as a special
stain. Conclusion: As per histopathological finding the lesion was diagnosed as GOC. [Sheth H Natl J Integr
Res Med, 2026; 17(1): 45-50, Published on Dated: 07/07/2026]

Effect Of Virtual Reality Distraction On Anxiety During Various Surgery Under Spinal Anaesthesia

2026-10-02T11:18:27+00:00

Background: Regional anaesthesia avoids general anaesthesia risks but can cause anxiety. Sedatives
like midazolam help but have side effects. Virtual Reality (VR) distraction might reduce anxiety without these
risks. Objective: Evaluate VR distraction versus midazolam sedation on patient satisfaction and anxiety during
spinal anaesthesia. Case Presentation: In this study, 60 patients were divided into VR (n=30) and sedation
(n=30) groups. Baseline demographics, intraoperative vital parameters, and postoperative satisfaction were
recorded. Primary outcomes were patient satisfaction on a 5-point Likert scale. Secondary outcomes included
satisfaction of surgeons and anaesthesiologists, and incidence of involuntary movements, desaturation,
apnea, and hemodynamic changes. Results: The VR group reported higher patient satisfaction (mean score
4.73 vs. 4.4, p=0.1) and anesthesiologist satisfaction (mean score 4.47 vs. 3.73, p=0.007). Apnea (3.33% vs.
20%, p=0.02) and desaturation (3.33% vs. 13.33%, p=0.04) were lower in the VR group, which also had fewer
intraoperative movements and less tachycardia. Conclusion: VR distraction during spinal anesthesia improves
patient and anesthesiologist satisfaction, reduces perioperative anxiety, and lessens hemodynamic
instability, offering a safe and effective non-pharmacological alternative for anxiety management in surgical
settings. [Patel V Natl J Integr Res Med, 2026; 17(1): 1-9, Published on Dated: 07/07/2026]

Clinico-Epidemiological Study Of Sexually Transmitted Diseases At Tertiary Care Centre

2026-10-02T11:28:54+00:00

Background: Sexually Transmitted Diseases (STDs) pose a significant threat to human health,
causing substantial psychosocial and economic burdens among young and sexually active adults. Factors such
as rapid population growth, rural-urban migration, commercial sex work and inadequate awareness have
contributed to the spread of STDs within communities. This study examines the patterns of STDs among
patients presenting to our hospital over a 10-year period. Aim: To study the clinico-epidemiological profile of
the patients with Sexually Transmitted Diseases. Material and Methods: This is retrospective study. This
included consecutive symptomatic STD patients presenting between January-2015 to December-2024.
Diagnoses were established through detailed history, clinical examination and relevant investigations.
Results: Most common affected age group was 21-30 years. Incidence of STD was high among Males
(79.05%). Married persons were more commonly affected as compared to unmarried. Herpes Genitalis was
the most common STD followed by Genital warts, Genital Molluscum Contagiosum. The Overall
seroprevalence of HIV among STD patients was 29.62%. Herpes Genitalis was the most common coinfection
among seropositive individuals. Conclusion: The proportion of viral STDs was higher compared to bacterial
STDs. Increase of viral STDs has been attributed to widespread use of broad- spectrum antibiotics,
asymptomatic shedding of virus and incurable nature of viral STDs. Since STDs are indicators of high -risk
sexual behaviour in the community and a major health burden with risk of development of HIV and other
consequences, prompt diagnosis and adequate treatment of STDs is necessary. [Patel H Natl J Integr Res
Med, 2026; 17(1): 10-14, Published on Dated: 07/07/2026]

Comparative Evaluation Of Antibacterial Efficacy Of Nonantibacterial Drugs - Diclofenac Sodium, Omeprazole And Cetirizine Against E. Faecalis When Used As An Intracanal Medicament: An In Vitro Study

2026-10-02T11:35:26+00:00

Background: Microorganisms, especially Enterococcus faecalis, play a major role in pulpal and
periapical diseases and often survive root canal treatment due to complex canal anatomy and biofilm
formation. Conventional intracanal medicaments like calcium hydroxide have limitations against resistant
bacteria, leading to interest in non-antibiotic drugs with antimicrobial properties. Drugs such as Diclofenac
sodium, Cetirizine, and Omeprazole have shown potential antibacterial and anti-inflammatory effects in
endodontics. Therefore, this study was conducted to compare the antimicrobial efficacy of Diclofenac
Sodium, Calcium Hydroxide, Cetirizine, and Omeprazole against E. faecalis at 24 hours and 7 days.Aim: This
study aimed to evaluate the antibacterial efficacy of non-antibacterial drugs—diclofenac, omeprazole, and
cetirizine—against Enterococcus faecalis when used as intracanal medicaments at time interval of 24 hr and
7 days in endodontic treatments. Settings and Design: An in-vitro comparative study. Materials and Method:
The study comprised of four test groups- Group – 1 [Ca (OH)2 (16mg/ml)], Group – 2 [Diclofenac sodium (400
mg/ml)], Group – 3 [Omeprazole (4 mg/ml)], Group – 4 [Cetirizine (2 mg/ml)], each group contained 10
samples, which were evaluated for antibacterial efficacy using agar well diffusion test. The experimental
specimens were then placed on agar plates inoculated with E. faecalis, and the area of inhibition was
calculated. Statistical analysis: Antibacterial efficacy was evaluated using multiple group comparison using
One-way Anova, Posthoc Tukey test and Paired t-test. Results: All the experimental groups exhibited
bacterial inhibition; however, group 2 exhibited highest antibacterial activity compared to group 1,3 and 4.
Conclusion: This study demonstrates the promising antibacterial efficacy of non-antibacterial drugs,
particularly diclofenac sodium, when used as intracanal medicament against Enterococcus faecalis,
highlighting its potential as an effective alternative in endodontic treatments. [Patel P Natl J Integr Res Med,
2026; 17(1): 15-21, Published on Dated: 07/07/2026]

Evaluation And Management Of Immediate Posttraumatic Facial Nerve Palsy At Sir T Hospital, Tertiary Care Centre In Bhavnagar

2026-10-02T11:45:44+00:00

Background: Facial nerve palsy following trauma, is an uncommon condition which occurs in 1.5%
patients of skull base fractures, majority of them due to road traffic accidents causing temporal bone
fractures. Indication and timing of facial nerve decompression for facial paralysis and anatomical extent of
decompression has been a subject of controversy for years. The aim of this study is to present prospective
review of 10 patients with immediate facial paralysis after trauma that underwent either surgical
decompression of facial nerve via trans mastoid approach or conservative management. Objectives-To know
age and sex wise distribution of immediate posttraumatic facial nerve palsy and to know most common grade
of presentation according to H-B scale and most common type of temporal bone fractures and segment of
facial nerve involved. To study outcome (within 1 month) of various modes of management of immediate
posttraumatic facial nerve palsy. Material And Methods: After approval from ethics committee, this
prospective cross-sectional study was carried out in 10 patients presented with immediate facial nerve palsy
due to trauma at ENT department of Sir T Hospital, Bhavnagar over a period of 1 year from July 2022 to June
2023. After taking consent, proper history was taken and time of RTA and time of presentation at ENT OPD
was separately noted. Patients were examined and graded using House and Brackman grading system. All
the patients were evaluated and treated either by conservative management (Injectable steroids with facial
physiotherapy) or surgical decompression via trans mastoid approach. Results: Most common age group
involved was the young adolescents (20-30years) who are more prone to RTA and traumatic injuries.
Numbers of males affected were more than females in our study. Tympanic segment of facial nerve was
found to be involved in maximum number of patients. Patients with transverse fracture of temporal bone
causing immediate posttraumatic facial palsy were found to have better prognosis with surgical
decompression. Patients with longitudinal fracture of temporal bone can go for either conservative
management or if no improvement found within 7days were taken for surgical decompression of facial nerve
via trans mastoid approach. Most of the patients who were managed surgically were found to have better
prognosis according to this study. Conclusion: We draw the conclusion from our study that early diagnosis
and surgical intervention significantly improved prognosis for immediate facial palsy following trauma. The
trans mastoid approach for facial nerve decompression can be utilized when trauma is clearly localized to the
tympanic or mastoid segment of facial nerve. Transverse fracture of temporal bone should be always treated
with immediate surgical decompression and in longitudinal fractures both conservative and surgical
management plays an important role. Appropriate post-operative management with oral steroids and
physiotherapy plays an important role in traumatic facial nerve palsy. [K A Natl J Integr Res Med, 2026; 17(1):
22-26, Published on Dated: 07/07/2026]

Bacteriological Profile And Antibiogram Analysis: A Retrospective Study From A Tertiary Care Hospital In North India

2026-10-02T12:29:23+00:00

Background: Healthcare-associated infections (HAIs) contribute significantly to morbidity,
mortality, and healthcare costs, particularly in developing countries. The rising prevalence of multidrug
resistant organisms necessitates continuous surveillance of local bacteriological profiles and antimicrobial
susceptibility patterns. Objectives: To determine the bacteriological spectrum and analyze antimicrobial
susceptibility patterns of clinical isolates from bloodstream, urinary tract, respiratory tract, and surgical site
infections in a tertiary care hospital. Materials and Methods: This retrospective observational study was
conducted in the Department of Microbiology at a tertiary care center in North India from July 2024 to June
2025. All culture-positive clinical samples were included. Bacterial identification was performed using
standard microbiological methods, and antimicrobial susceptibility testing was done using the Kirby–Bauer
disk diffusion method. Results were interpreted as per Clinical and Laboratory Standards Institute (CLSI)
guidelines. Results: A total of 916 isolates were analyzed. Gram-negative organisms predominated across all
infection types. Escherichia coli and Klebsiella pneumoniae were the most common pathogens. Colistin
showed 100% sensitivity among Gram-negative isolates. Carbapenems demonstrated moderate sensitivity,
whereas high resistance was observed to cephalosporins and fluoroquinolones. Gram-positive organisms,
including Staphylococcus aureus and Enterococcus species, showed 100% sensitivity to vancomycin, linezolid,
and daptomycin. In urinary tract infections, E. coli showed high sensitivity to nitrofurantoin and fosfomycin.
Conclusion: Gram-negative bacteria predominate in HAIs with increasing antimicrobial resistance. Regular
surveillance and institution-specific antibiograms are essential for guiding empirical therapy and
strengthening antibiotic stewardship. [Tiwari U Natl J Integr Res Med, 2026; 17(1): 39-44, Published on Dated:
07/07/2026]

The Spectrum Of Infectious Dermatoses In Children: A Clinical Study Of 120 Cases

2026-10-10T09:12:53+00:00

Background & Objective: Skin diseases are significant health problems in the paediatric age group,
affecting not only the growth and development of children but also causing considerable morbidity. Bacteria,
fungi, and viruses are responsible for many of these infections, with Fungal playing a major role. The aim is
to assess the prevalence and clinical features of various infectious paediatric dermatoses in rural tertiary care
center. Material and Method: Study was conducted on 120 children with infectious dermatoses aged below
14 years attending the Department of D.V.L. Bhavsinhji General hospital (GMERS) Porbandar. Result: A total
of 120 cases were studied, showing a male preponderance (61.67%) and M: F 1.60:1 ratio. The most common
infections observed in the present study were fungal infection followed by Bacterial infections and viral
infections. Conclusion: The majority of infectious skin conditions were fungal infections (56.67%), with the
most common being dermatophytosis (52.94% of fungal infections). Bacterial infections comprised 36.66%
of all infections, with the most common being Impetigo (27.27%). Viral infections accounted for 37% of all
infections, with Molluscum contagiosum being the most common (39.1%). The findings indicated an upward
trend in fungal infections. [Pandit R Natl J Integr Res Med, 2026; 17(1): 33-36, Published on Dated:
07/07/2026]