Detection and Utility of CRP in Neonatal Patients as an Early Marker
Detection and Utility of CRP in Neonatal Patients as an Early Marker
DOI:
https://doi.org/10.70284/njirm.v8i2.1203Keywords:
CRP, Early detection, NeonatesAbstract
Background &Objectives:1) Detection of CRP in neonatal patients.2) Analyzing and utility of CRP as an early marker to decrease the mortality and morbidity among neonates.Methods: This is retrospective study spanning from 01.05.2016 to 31.08.2016. Serum sample of neonates with clinical features of tachypnoea, tachycardia, hypotonia, oliguria and poor responsiveness etc. were sent to the laboratory for CRP testing by the clinicians. A total of 5870 serum samples of neonates were tested for CRP by using RECKON DIAGNOSTIC KIT based on latex agglutination, those which tested positive were subjected to determination of titre. RESULT:A total 5870 neonatal samples were received out of which 4340 (73.93%) tested positive. Titre of positive samples ranged from 0.6 mg/dl to 19.2mg/dl. Interpretation&Conclusion: CRP has high sensitivity and specificity for establishing the diagnosis of neonatal diseases and can be taken as an early marker. It is preferable to other markers viz, IL-2, IL-6, INF Gamma, TNF-alfa, and Cytokines because of its low-cost benefit, easy availability and convenient testing methods. It is also better than culture methods like blood culture because of early result availability. Therefore it can be used commonly for early detection of neonatal conditions.[Sarita NJIRM 2017; 8(2):59-61]
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