Drug Utilization Pattern Of Antimicrobial Agents In Dental Outpatients Of A Tertiary Care Teaching Rural Hospital
Drug Utilization Pattern Of Antimicrobial Agents
Keywords:
Dentistry, antimicrobials, drug utilization studyAbstract
Aim: To study drug utilization pattern of antimicrobial agents in various outpatient departments of a tertiary care teaching rural dental hospital. Methods: A prospective-observational study was carried out in 200 patients from January 2014 to March 2014. Relevant information was obtained from the interview as well the hospital case record. Structured and pre-tested format was used for compiling the data. Results: The majority of the patients (51.5%) were in age group 41 to 60 years. Common conditions for antibiotic use included periodontal diseases (46.5%), endodontic diseases (38.5%) and dental caries (21.5%).Five antimicrobial drug formulations were used leading to a total of their 253 drug uses. Amoxicillin alone (64%) was the most commonly prescribed antimicrobial formulation followed by amoxicillin plus clavulanic acid (31.5%), metronidazole (26.5%), ofloxacin plus ornidazole (3%) and doxycycline (1.5%). The average number of antimicrobials prescribed per patient was 1.61. The average duration of antimicrobial was found to be minimum 3 days to maximum 5 days. Except ofloxacin plus ornidazole, all of the prescribed antimicrobials have been included in the WHO Model List of Essential medicines. 50.59% and 49.40% of total antimicrobial drug formulations were prescribed by generic and brand names respectively. Conclusions: Drug utilization data can help to formulate appropriate clinical guidelines for drug use and facilitate rational use of medicines in population. [Patel N NJIRM 2014; 5(3):42-45]
References
2. Poveda – Roda R, Bagan JV, Sanchis – Bielsa JM, Carbonell – Pastor E. Antibiotic use in dental practice, a review. Med Oral Patol Oral Cir Bucal. 2007; 12: 186-192
3. Palmer NAO, Pealing R, Ireland RS, Martin MV. A study of therapeutic antibiotic prescribing in National Health Service general dental practice in England. Br Dent J. 2000;188 (10): 554-558.
4. Sharma HL and Sharma KK. Dental pharmacology. New Delhi: Paras medical publisher; 2014. P.348
5. Select Committee on Science and Technology (1998). Resistance to antibiotics and other antimicrobial agents. London: HMSO.
6. Pallasch TJ. Antibiotics in endodontics. Dent Clin North America. 1979; 23: 737-746.
7. Abbott PV, Hume WR, Pearrmar JW. Antibiotics and endodontics. Australian Dent J. 1990; 35: 50-60.
8. J. F. Siqueira Jr., I. N. Rocas, and M. G. Silva, “Prevalence and clonal analysis of Porphyromonas gingivalis in primary endodontic infections,†Journal of Endodontics, vol. 34, no. 11,pp. 1332–1336, 2008.
9. Manasa CR, Dass AP. Prescribing patterns of antibiotics in dental practice. International Journal of Basic and Applied Medical Sciences 2013; 3(2):336-339.
10. Rauniar GP, Das BP. A prospective study of dental disease pattern and drug utilization at the dental department of a tertiary care teaching hospital in eastern Nepal. Journal of Nepal Medical Association 2001; 40:6-11.
11. Salman MT, Khan FA. Drug Prescribing Pattern in Dental Teaching Hospital. JK Science 2009; 11(2):107
12. Kulkarni MD, Baig MS. Drug utilization pattern in OPD of government dental college and hospital, Aurangabad. International Journal of Basic & Clinical Pharmacology | 2013; 2(1):69-70
13. Dar-odeh NS, Abu- Hammad OA. Antibiotic prescribing practices by dentists: a review. Therapeutics and Clinical Risk Management 2010; 6:301-306
14. Medical Council of India. The Indian Medical Council (Professional Conduct, Etiquette and Ethics) Regulations, 2002 inter-alia prescribes as under regarding use of generic names of drugs vide clause 1.5. Online Available from: http://www.mciindia.org/tools/announcement/Circular_Ethics_21.01.2013.pdf Accessed 15 Nov 2013
15. Health and family welfare, Government of Gujarat, GR No BGT/10/2013/G issued on 1 Jul 2013
