Assessment of Autonomic Functions in Hypothyroidism
Assessment of Autonomic Functions in Hypothyroidism
Keywords:
Autonomic Function, Hypothyroidism, HormoneAbstract
Disturbances in autonomic functions have been observed in many diseases including hormonal disorder (Banisters 1983). Present study was undertaken to study the autonomic functions in thyroid hormones on in 60 untreated hypothyroid patients, using Valsalva and deep breath test, cold pressor test, hand grip test and orthostatic test to assess the sympathetic and parasympathetic reflexes. The results obtained in this study were compared with the age sex matched controls. It is concluded that the sympathetic response is not altered in the hypothyroid cases while reflex vagal activity is significantly reduced.
References
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vagal & sympathetic efferents: Study of centrally induced reactions. J. Auton. Nerve. Syst. 3: 483- 501.
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2. Poliker R, Burger AG, Scherer U, Nicod P. (1993). The thyroid and the heart. Ciculation.87:1435-1441. Rundles, RW (1945). Diabetic neuropathy. General review with report of 125 cases. Medicine 24, 111-60.
3. Levey GS, Klien I. (1990). Catecholamine thyroid interaction and the cardiovascular manifestation of hyperthyroidism. Am. J. Med. 88:642-46.
4. Christensen NJ (1973). Plasma nor adrenaline and adrenaline in patients with thyrotoxicosis and myxoedema. Clin. sci. 45:163.
5. Kollai, B. and Kollai, M. (1988). Reduced cardiac vagal excitability in hyperthyroidism. Brain Res. Bull. 20(6) 7850790.
6. Howitt G, Rowlands DJ, Leung DT, Logan WE. (1968). Myocardial contractility, and the effects of beta-adrenergic blockade in hypothyroidism and hyperthyroidism. Clin Sci; 34:485.
7. Vander Schoot, J.B., Moran, N.C. (1965). An experimental evaluation of the reported influence of thyroxin on the cardiovascular effects of catecholamine, J. Pharmacology Exp. Ther. 149,336-345.
8. Grossman W, Robin NI, Johnson LW, Brooks H, Selenkow HA, Dexter L. (1971). Effect of beta blockade on the peripheral manifestations of thyrotoxicosis. Ann Intern Med; 74-875.
9. Levin AB, (1966). A simple test of Cardiac function based upon the heart rate changes induced by the Valsalva maneuver. Am. J. Cordial. 18:90-99.
10. Hutchinson’s clinical methods (1989)365-366.
11. Koizumi, K. Kollai, M. (1981). Control of reciprocal & nonreciprocol & actions of
vagal & sympathetic efferents: Study of centrally induced reactions. J. Auton. Nerve. Syst. 3: 483- 501.
12. Dratman, M.B., Goldman, M, Crutchfield. F.L., Gordon, J. T. (1982). Nervous system role of iodocompounds in blood pressure regulation. Life sci. 30:611-619.
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Published
2010-03-31
How to Cite
kumar, S. (2010). Assessment of Autonomic Functions in Hypothyroidism: Assessment of Autonomic Functions in Hypothyroidism. National Journal of Integrated Research in Medicine, 1(1), 4–7. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/44
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