A Prospective Study To Evaluate The Efficacy Of Platelet-Rich Plasma With Microneedling In Androgenetic Alopecia

Abstract

Background: Platelet-Rich Plasma(PRP) has better efficacy when combined with dermaroller.
Dermaroller stimulates proliferation and differentiation of stem cells in the hair follicles bulge are a via
multiple molecular mechanisms. Methods: Platelet-rich plasma (PRP) is a simple and safe procedure, which has
been used for soft tissue and wound healing. PRP has been used in dermatology for skin rejuvenation and alopecia.
They have emerged as new non-surgical treatment modalities for AGA, with minimal side effects and
good safety profile. It is a promising treatment option in patients who cannot afford hair
transplantation. Results: Total 90 patients included in this study, 15 were female and 75 were male
patients. Their age varied from 22 to 48 years with a median age of 32 years. According to subjective scores
(PSS), eight patients had excellent results, forty two had very good, 26 had good, 8 had fair results, and 6
(10%) did not have any response. Objective assessment scores (OAS) showed that eight patients had
excellent results, 42 had very good, 26 had good, 8 had fair results, and 6 did not have any response.
Conclusion: The effect of microneddling by dermaroller with PRP has shown a considerable increase in hair
counts in the majority of the subjects in present study. Present study showed excellent results in patients
treated with Plapelet-Rich Plasma and Dermaroller. It is really a promising therapeutic modality with
an excellent safety profile and patient satisfaction.[Shah R, Natl J Integr Res Med, 2025; 16(1):14-18,
Published on Dated: 26/02/2025]