Nonsyndromic Multiple Odontogenic Keratocysts: A Case Report
Nonsyndromic Multiple Odontogenic Keratocysts
Keywords:
Multiple odontogenic keratocysts; Non-syndromic; Gorlin Goltz syndromeAbstract
Multiple Odontogenic keratocysts (OKCs) are one of the most frequent features of nevoid basal cell
carcinoma syndrome (NBCCS). NBCCS is a genetic disorder transmitted by an autosomal dominant gene with
variable expressivity, which is important to recognize when a patient has multiple OKCs. It is linked with
mutation in the PTCH gene. Partial expression of the gene may result in occurrence of only multiple OKC. We
hereby report a case of multiple OKCs in a non – syndromic patient and highlight the general practitioner the
importance of diagnosing the disease and enforcing a strict long-term follow-up whenever such a case is
identified.
References
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keratocysts: report of a case. J Can Dent Assoc
2006 Sep; 72(7):651-6.
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Gopalkrishnan Non- Syndromic Recurrent
Multiple Odontogenic Keratocysts: A CaseReport. Journal of Dentistry, Tehran University
of Medical Sciences, Tehran, Iran 2011; Vol. 8,
No.2
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odontogenic keratocysts with Diverse histologic
features in a non- syndromic patient. Pravara
Med Rev 2010; 5(3):35-7.
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Keerthilatha M. Pai, Geetha V. Non-syndromic
multiple odontogenic keratocysts: report of
case. Rev ClÃn Pesq Odontol. 2008; 4(3):193-9.
7. Lindeboom JA, Kroon FH, De Vires J, Van den
Akker HP. Multiple recurrent and De novo
Odontogenic keratocysts Associated with oralfacial-
digital syndrome. Oral Surg Oral Med
Oral Pathol Oral Radiol Endod. 2003; 95(4):458-
62.
8. Carr RJ, Green DM. Multiple odontogenic
keratocysts in a patient with type II (mitis)
Ehler-Danlos syndrome. Br J Oral Maxfacial
Surg. 1988; 26(3):205-14.
9. Connor JM, Evans DA, Goose DH. Multiple
odontogenic keratocysts in a case of the
Noonan syndrome. Br J Oral Surg. 1982;
20(3):213-6.
10. Neville BW, Damm DD, Allen CM, Bouquot JE.
Oral and maxillofacial pathology. 2nd ed.
Philadelphia: Saunders; 2002.
11. Todd R, August M. Molecular approachesto the
diagnosis of sporadic and nevoid basal cell
carcinoma syndrome associated odontogenic
keratocysts. Oral maxillofacial Surg Clin N Am
2003; 15(3):447-61.
12. Woolgar JA, Rippin JW, Browne RM. The
odontogenic keratocyst and its occurrence in
the nevoid basal cell carcinoma syndrome. Oral
Surg Oral Med Oral Pathol 1987; 64(6):727–30.
13. Yeo JF, Loh FC. Multiple odontogenic
keratocysts of the jaws Case report. Aust Dent J
1989; 34(6):503–6.
14. A. Habibi, N. Saghravanian, M. Habibi and E.
Mellati, Keratocystic odontogenic tumor: a 10-
year retrospective study of 83 cases in an
Iranian population, J Oral Sci 2007; 49: 229–35.
15. Dominguez FV, Keszler A. Comparative study of
keratocysts, associated and nonassociated with
nevoid basal cell carcinoma syndrome. J Oral
Pathol. 1988; 17(1):39-42.
16. L. Zhang, Z.J. Sun, Y.F. Zhao, Z. Bian, M.W. Fan
and Z. Chen, Inhibition of SHH signaling
pathway: molecular treatment strategy of
odontogenic keratocyst. Med Hypotheses
2006; 67:1242–44.
management of recurrent keratocysts in basalcell
naevus syndrome. Aust Dent J 1997;
42(6):399–403.
2. R B Brannon. The odontogenic keratocyst. A
clinicopathologic study of 312 cases.Part I.
Clinical features. Oral Surg Oral Med Oral
Pathol. 1976 Jul; 42 (1):54-72.
3. Auluck A, Suhas S, Pai KM. Multiple odontogenic
keratocysts: report of a case. J Can Dent Assoc
2006 Sep; 72(7):651-6.
4. AR. Bartake, NG. Shreekanth , S. Prabhu , K.
Gopalkrishnan Non- Syndromic Recurrent
Multiple Odontogenic Keratocysts: A CaseReport. Journal of Dentistry, Tehran University
of Medical Sciences, Tehran, Iran 2011; Vol. 8,
No.2
5. Rudagi B M, Kharkar V R, Kini Y. Multiple
odontogenic keratocysts with Diverse histologic
features in a non- syndromic patient. Pravara
Med Rev 2010; 5(3):35-7.
6. Amar A. Sholapurkar, Reddy MallelaVarun,
Keerthilatha M. Pai, Geetha V. Non-syndromic
multiple odontogenic keratocysts: report of
case. Rev ClÃn Pesq Odontol. 2008; 4(3):193-9.
7. Lindeboom JA, Kroon FH, De Vires J, Van den
Akker HP. Multiple recurrent and De novo
Odontogenic keratocysts Associated with oralfacial-
digital syndrome. Oral Surg Oral Med
Oral Pathol Oral Radiol Endod. 2003; 95(4):458-
62.
8. Carr RJ, Green DM. Multiple odontogenic
keratocysts in a patient with type II (mitis)
Ehler-Danlos syndrome. Br J Oral Maxfacial
Surg. 1988; 26(3):205-14.
9. Connor JM, Evans DA, Goose DH. Multiple
odontogenic keratocysts in a case of the
Noonan syndrome. Br J Oral Surg. 1982;
20(3):213-6.
10. Neville BW, Damm DD, Allen CM, Bouquot JE.
Oral and maxillofacial pathology. 2nd ed.
Philadelphia: Saunders; 2002.
11. Todd R, August M. Molecular approachesto the
diagnosis of sporadic and nevoid basal cell
carcinoma syndrome associated odontogenic
keratocysts. Oral maxillofacial Surg Clin N Am
2003; 15(3):447-61.
12. Woolgar JA, Rippin JW, Browne RM. The
odontogenic keratocyst and its occurrence in
the nevoid basal cell carcinoma syndrome. Oral
Surg Oral Med Oral Pathol 1987; 64(6):727–30.
13. Yeo JF, Loh FC. Multiple odontogenic
keratocysts of the jaws Case report. Aust Dent J
1989; 34(6):503–6.
14. A. Habibi, N. Saghravanian, M. Habibi and E.
Mellati, Keratocystic odontogenic tumor: a 10-
year retrospective study of 83 cases in an
Iranian population, J Oral Sci 2007; 49: 229–35.
15. Dominguez FV, Keszler A. Comparative study of
keratocysts, associated and nonassociated with
nevoid basal cell carcinoma syndrome. J Oral
Pathol. 1988; 17(1):39-42.
16. L. Zhang, Z.J. Sun, Y.F. Zhao, Z. Bian, M.W. Fan
and Z. Chen, Inhibition of SHH signaling
pathway: molecular treatment strategy of
odontogenic keratocyst. Med Hypotheses
2006; 67:1242–44.
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Published
2012-10-31
How to Cite
Parikh, D. R. (2012). Nonsyndromic Multiple Odontogenic Keratocysts: A Case Report: Nonsyndromic Multiple Odontogenic Keratocysts. National Journal of Integrated Research in Medicine, 3(4), 148–151. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/382
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