Pattern Of Bacterial Pathogens And Their Susceptibility Isolated From Surgical Site In Tertiary Care Hospital Of Western India
Pattern Of Bacterial Pathogens And Their Susceptibility Isolated From Surgical Site
Keywords:Surgical site infections,Injudicious use of Antibiotics, Antibiotic prophylaxis policy.
Background: The emergence of multidrug resistant Bacterial pathogens in hospitals and associated risk factors are strenuous task for surgeons to treat SSIs.Isolation of MRSA and MDROstrains are an existing problem with a rising trend in Indian hospitals. To study the microbial profile and their susceptibility pattern & the risk factors of SSIs and revising antibiotic prophylaxis policy to reduce injudicious use of antimicrobial agents. Material And Methods: This studyincluded 465 post of patients of general surgeries held at Tertiary care teachingcenter, western side of India from July 2017 to August 2018.Samples were collected using sterile cotton swab and processed as per standard operative procedures in appropriate culture media and susceptibility testing was done using Kirby-Bauer disc diffusion technique. After incubation plates were examined and interpreted according to CLSI guidelines. Result: Among465patients SSIs were identified in 32 (6.88%) patients. In this study, predominant organism isolated was E. coli (40.6%), followed by Klebsiella spp. (31.2%), Pseudomonas aeruginosa (25.0%), Staphylococcus aureus (3.13%). Pan-antibiotic resistance was noted among 9(29.03%) gram negative rods. Conclusion: Overall, resistance to cephalosporin group of antibiotics (including latest 3rd generation) & penicillin group is increased, so rather than moving on to costlier antibiotics, aminoglycosides (amikacin/gentamycin) and fluoroquinolones (levofloxacin) are the better preferred drugs. [Sathwara N Natl J Integr Res Med, 2020; 11(5):41-49]