Cleidocranial Dysplasia With Dens Invaginatus: A Report Of Two Cases

Cleidocranial Dysplasia With Dens Invaginatus: A Report Of Two Cases

  • Dr. Shilpa J. Parikh MDS, Professor,Oral Medicine And Radiology, GDCH, Ahmedabad
  • Dr. Monali N. Prajapati PG Student, MDS,Oral Medicine And Radiology, GDCH, Ahmedabad
  • Dr. Annu D. Verma PG Student, MDS,Oral Medicine And Radiology, GDCH, Ahmedabad
  • Dr. Jigna S. Shah Professor And Head Of Department, Oral Medicine And Radiology, GDCH, Ahmedabad
Keywords: Autosomal Dominant, Cleidocranial Dysplasia, Dens Invaginatus

Abstract

Background: Cleidocranial dysplasia (CCD) is an autosomal dominant malformation syndrome affecting bones and teeth. It has been demonstrated that mutation of the RUNX2 gene which controls osteoblastic differentiation, appropriate osteogenesis and odontogenesis via participation in odontoblast differentiation, enamel organ formation and dental lamina proliferation is responsible for CCD. The dental abnormalities associated with CCD are often the reason for diagnosis in mildly affected individuals. Here we present two cases of cleidocranial dysplasia with radiographic analysis, both presenting with a rare dental anomaly; dens invaginatus. [Parikh S Natl J Integr Res Med, 2020; 11(4):94-98]

Published
2020-09-01
How to Cite
Dr. Shilpa J. Parikh, Dr. Monali N. Prajapati, Dr. Annu D. Verma, & Dr. Jigna S. Shah. (2020). Cleidocranial Dysplasia With Dens Invaginatus: A Report Of Two Cases: Cleidocranial Dysplasia With Dens Invaginatus: A Report Of Two Cases. National Journal of Integrated Research in Medicine, 11(4), 94-98. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/2865
Section
Case Report