Histopathology of Tumor and Tumor like conditions of Blood Vessels and Lymphatics
Histopathology of Tumor and Tumor like conditions of Blood Vessels and Lymphatics
Keywords:
Vascular tumors, AV malformation, Lymphatic vessels, Hemangioma, AngiosarcomaAbstract
Introduction: Vascular Neoplasms are divided into benign, intermediate and malignant subtypes according to WHO classification. The majority of vascular tumors are of benign nature. The aim of this study is to observe the histopathological pattern of tumors and tumor like conditions of blood vessels and lymphatics. Material and methods: An observational study was done over a period of one and half years (Jan 2017 to June 2018) at the Histopathology Department of AMC MET Medical College, L.G. Hospital, Maninagar, Ahmedabad which is a tertiary care hospital of East Ahmedabad. There were 75 histopathological cases of vascular tumors & tumor like conditions. Results: Out of 75 cases, 63 were benign, 2 were malignant and 10 were arteriovenous (AV) malformation. The majority of tumors were located in Head & Neck region (n=48), followed by 13 in Trunk region & 14 in extremities. There were 28 cases of pyogenic granuloma, 18 cases of capillary hemangioma, 9 cases of cavernous hemangioma, 1 case of lymphangioma, 2 cases of epithelioid hemangioma, 5 cases of cystic hygroma, 2 cases of angiosarcoma and 10 cases of AV malformation. Majority of the patients were males. Conclusion: Benign lesions were the most common variety amongst tumors and tumor like conditions of blood vessels and lymphatics. Among the benign vascular tumors, Granuloma Pyogenicum was the commonest followed by capillary hemangioma. Histological diagnosis of AV malformation helps in proper management of the condition. [Chakrabarti B Natl J Integr Res Med, 2019; 10(4):1-5]
References
2. Robbins & Cotran. Blood Vessels. In: Pathologic Basis of Disease. 8th ed. RELX India Private Ltd.; p. 515–6.
3. Lever’s. Vascular Tumors. In: Histopathology of Skin. 10th ed. Lippincott Williams & Wilkins; p. 1022.
4. Enzinger & Weiss. Malignant Vascular Tumors. In: Soft Tissue Tumors. 6th ed. Mosby; 2013. p. 703–5.
5. Kapuria D, Patel P, Shah A. Histopathological Study of 100 Cases Of Vascular Tumors. Natl J Med Res. 2012 Jun;2(2).
6. Kalyani DD, Bharatarao DN. Histopathological Study of Vascular Lesions. J Dent Med Sci. 2017 Nov;16(11):47–52.
7. Mills S. Nonmelanocytic tumors. In: Sterberg’s Diagnostic Surgical Pathology. 6th ed. Lippincott Williams & Wilkins; 2015. p. 64–7.
8. Juan R. Cardiovascular System. In: Rosai and Ackerman’s Surgical Pathology. 9th ed. 2004. p. 2285–6.
9. Fletcher C. Vascular Tumors. In: Diagnostic Histopathology Of Tumors. Elsevier; 2013. p. 66–7, 515–6.
10. Pawane P, Anshu, Gangane N. Hemangiomas versus arterio-venous malformations: role of elastic stains and mast cell density. Indian J Pathol Microbiol. 2014 Jun;57(2):191–5.
