Pharmacoepidemiological Profile Of Diagnosed Cases Of Infertility (A Cross Sectional Observational Study)

Pharmacoepidemiological Profile Of Diagnosed Cases Of Infertility

Abstract

Background: The incidence of primary and secondary infertility is going to increase significantly. Amidst many causes, obesity is considered to be the most important cause. The aim of this work was to identify the epidemiological profile and prescribing pattern of drug therapy for women suffering from infertility. Methodology: Cross sectional observational study was conducted at multispeciality private hospital over a period of six months. Epidemiological details and drugs prescribed for infertility were recorded in a predesigned structured case record form. The age wise distribution and BMI wise distribution was prepared. Categorical data were expressed as number and percentage, and numerical data as mean and standard deviation. Results: There was nearly equal distribution of infertility in age group of 25-30 years (66,38.37%) and 30-35 years (62,36.05%)Majority of the females were in age group of 78 females (45.35%) were overweight and obese while rest were normal weight (73,42.44%) or underweight (21,12.21%). 116 (67.44%) were having primary infertility while 56 females (32.56%) were having secondary infertility. 41 females (53.80%) were having associated systemic illnesses. Clomiphene citrate, Metformin, Orlistat were prescribed in all the cases. Conclusion: Rate of infertility increases with age in both normal weight and obese females. No statistically significant differences between primary and secondary infertility in normal weight and obese persons were found. Associated systemic illnesses were higher in obese females, espically genital tuberculosis. Clomiphene citrate, Metformin and Orlistat are commonly prescribed agents for the management of infertility. Further research is required to clarify the role of Glucocorticoids and aspirin therapy as an aid to implantation. [Dave D Natl J Integr Res Med, 2019; 10(2):61-68]