A Study Of Factors Associated With Anaemia In HIV Infected Individuals

Abstract

Background: Anaemia is the most common hematologic manifestation seen in HIV infection. The etiologies of anaemia may be different from the general population. Objectives: to study the etiology of anaemia in HIV positive individuals. Material & Methods: A cross-sectional study will be carried out on 100 consecutive HIV patients in different stages of disease attending the Department of Medicine, Vijayanagara Institute of Medical Sciences Bellary, Karnataka during the period of 18 months from October 2014 to may 2016 applying following inclusion and exclusion criteria. Results: Mean age of the patients was 39 years and 72% of the subject were male. CD4 count was lesser than 200/μl in 61% of patients and was greater than 200 in 39%of the patients. 42% patient had moderate grade anaemia and 58% had severe grade anaemia patient mild grade anaemia was excluded. 54% of patient had anaemia due to chronic disease, 12% had iron deficiency anaemia, 11% had anaemia due to vitamin.B12 deficiency, 22 % had anaemia due to zidovudine induced anaemia and 1patient had anaemia due Hemolysis. There was significant difference in hemoglobin values among patients who had CD4 count less than 200/μl (mean Hb 6.387gm/dl) and CD4 count greater than 200/μl (mean Hb 7.469gm/dl) (p=0.001). ). There was positive correlation between CD4 count and hemoglobin (r=0.2637, p=0.001) There was positive correlation between Vitamin B12 levels and CD4 count( r-0.2748) or (r-0.271) but relationship is weak. Conclusion: It was concluded that mean age of the patients was 39 years. the patients included in this study had advanced disease. Most of the patient had anaemia of chronic disease when compared to other etiology. [Naik K Natl J Integr Res Med, 2019; 10(2):48-51]