Use of geneXpert in the diagnosis of paediatric tuberculosis – A retrospective study in Northern Maharashtra

Use of geneXpert in the diagnosis of paediatric tuberculosis – A retrospective study in Northern Maharashtra

Authors

  • Sunil Lilani Associate Professor, Dept. of Microbiology, Shri Bhausaheb Hire Govt. Medical College, Dhule, Maharashtra
  • Pooja Shah Tutor, Dept. of Microbiology, Govt. Medical College, Akola, Maharashtra
  • Madhuri Suryawanshi Assistant Professor, Dept. of Microbiology, Shri Bhausaheb Hire Govt. Medical College, Dhule, Maharashtra
  • M. N. Dravid Professor and Head, Dept. of Microbiology, Shri Bhausaheb Hire Govt. Medical College, Dhule, Maharashtra

Keywords:

GeneXpert, MDR-TB, 2016-2017, Pediatric

Abstract

Introduction:Tuberculosis (TB) is an important cause of childhood morbidity and mortality. Prevalence of childhood TB has been reported to be between 3 and 25% in different countries. GeneXpert gives results in approximately 4 hours and hence it is widely used. Aims and objectives:
1. To study the occurrence of tuberculosis in pediatric patients.
2. To study the age and sex predominance of TB.
3. To study occurrence of MDR-TB(Multi Drug Resistant) in pediatric age group.
Material and Methods:Sample testing was done using GeneXpert system as per manufacturer’s guidelines from January 2016-December 2017. Results:Total 186 samples were suspected for pediatric TB from January 2016-December 2017. 11.48% samples were positive for TB by geneXpert. 9-12 years age group was most commonly affected(57.14%). Males were more affected than females(2:1). Sputum sample was most common sample obtained followed by gastric lavage and pleural fluid. MDR TB was seen in 14.29% cases. Conclusion: GeneXpert proves to be important method in detection of tuberculosis with early results.

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Published

2018-11-01

How to Cite

Lilani, S., Shah, P., Suryawanshi, M., & Dravid, M. N. (2018). Use of geneXpert in the diagnosis of paediatric tuberculosis – A retrospective study in Northern Maharashtra: Use of geneXpert in the diagnosis of paediatric tuberculosis – A retrospective study in Northern Maharashtra. National Journal of Integrated Research in Medicine, 9(5), 20–22. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/2420

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