Hepatitis B Immunization Status of Health Care Personnel

Hepatitis B Immunization Status of Health Care Personnel

Authors

  • Khristi Purvi Resident doctor, Department of Microbiology, Pramukhswami Medical College, Karamsad, Anand-388325
  • Rupal Patel Associate Professor, Department of Microbiology, Pramukhswami Medical College, Karamsad, Anand-388325
  • Chirag Modi Associate Professor, Department of Microbiology, Pramukhswami Medical College, Karamsad, Anand-388325

Keywords:

Health Care Personnel, HBV, anti-HBs antibody titre

Abstract

Background & objectives: Post-vaccination anti-HBsAg antibody titer measurements among Health Care Personnel (HCP) are not being done routinely at present. The present study was carried out to assess the post vaccination immunization status of HCP and to find an association between demographic & host factors and level of immunity. Methods: Cross-sectional prospective study was conducted at Shree Krishna Hospital, Karamsad. Information on Hepatitis B Virus (HBV) vaccination status and demographic details of HCP were collected using a structured proforma through verbal interviews and hospital information system. Anti-HBs antibody titre was determined by Enzyme Linked Immunofluorescent Assay (ELFA). Results : They were analysed using Pearson Chi2 test and Fisher’s exact test. Results: Among 505 participants, 96.4% developed protective antibody titres (≥ 10 mIU/ml) after primary vaccination. Following revaccination of participants with insufficient titres, 100% developed protective antibodies. There were no non-responders in the study. There was a significant association between anti-HBs antibody titres and duration after last dose of vaccine (p = 0.01) whereas no correlation was found between antibody titres and gender, age group, BMI & category of HCP. conclusions: HBV vaccination showed an excellent response following primary vaccination. For HCP with insufficient titres after primary vaccination, re-vaccination and re-testing is recommended.[Khristi P,Natl J Integr Res Med, 2018; 9(4):37-42]

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Published

2018-08-31

How to Cite

Purvi, K., Patel, R., & Modi, C. (2018). Hepatitis B Immunization Status of Health Care Personnel: Hepatitis B Immunization Status of Health Care Personnel. National Journal of Integrated Research in Medicine, 9(4), 37–43. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/2379

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Original Articles