Assessment of Nutritional status in Hyperthyroidism patients
Assessment of Nutritional status in Hyperthyroidism patients
DOI:
https://doi.org/10.70284/njirm.v4i5.2226Keywords:
Hyperthyroidism, Thyroid Stimulating Hormone (TSH), triiodothyroinine (T3) , tetraiodothyronine (T4), nutritional status, multivitaminsAbstract
Introduction: Hyperthyroidism often referred to as overactive thyroid, is a type of thyrotoxicosis, a hypermetabolic clinical syndrome which occurs when there are elevated serum levels of T3 and/or T4. There are very less studies on the nutritional deficiencies related to hyperthyroidism. Methods: Quantitative determination of Thyrotropin (TSH), triiodothyroinine (T3) and tetraiodothyronine (T4) was analyzed along with nutritional analysis of dietary nutrients like carbohydrate, proteins, fat, vitaminA, B1, B2, C, niacin, etc. Biostatistical analysis and correlations were analyzed by using Graph Pad prism software. Results: The mean intake of nutrients in Hyperthyroid and control groups are: Carbohydrate (147.9 ± 41.89 g, 218.3 ± 100.0 g), Thiamin (0.567 ± 2.850 mg, 1.051 ± 0.470 mg), Riboflavin (0.590 ± 0.341 mg, 1.121 ± 0.415 mg), Niacin (7.560 ± 2.346 mg , 11.59 ± 3.571 mg), pyridoxine (0.066 ± 0.262 mg , 0.317 ± 0.627 mg), Vitamin B1 (0.087 ± 0.205 μg, 0.199 ± 0.306 μg), Folacin (130.0 ± 36.57 μg , 143.4 ± 57.29 μg) and the mean values of all these nutrients were not optimum as recommended by ICMR. Conclusion: We should all be aware of the nutritional deficiencies encountered in hyperthyroidism and hence we can provide considerable support by eliminating adverse influences and normalizing the nutritional status by including multivitamins , antioxidants, etc. along with daily antithyroid drugs.
References
3. Adapted from the Pharmaceutical Journal; Vol 265 No 7109; 240-244.
4. Kochupillai N. Clinical Endocrinology in India. Curr Sci 2000 ; 79:1061-7.
5. Lincy K. Skaria, Purnima Dey Sarkar, Gopinath Agnihotram. Thyroid dysfunctions in tribal women of Bastar region of Chattisgharh, India. Thyroid Science 6(6): 1-5, 2011.
6. Gharib H., Ryan R.J, Mayberry W.E, and Hockett T., Radioimmunoassay for Triiodothyronine (T3): Affinity and Specificity of Antibody for T3, J Clinical Endocrinol. 33, 509 (1971).
7. Chopra I.J. Ho R. S. and Lam R. An improved Radioimmunoassay of triiodothyronine in human serum, J. Lab Clinical Med 80, 729 (1971).
8. Sterling L., Diagnosis and Treatment of Thyroid Diseases, Cleveland CRC Press, p. 9-51 (1975).
9. Barker S.B., Determination of Protein Bound Iodine, Journal Biological Chemistry 173,175 (1948).
10. Young D. S., Pestaner L.C., and Gilberman U., Effects of Drugs on Clinical Laboratory Tests, Clinical Chemistry 21, 3660 (1975).
11. Nutritive value of Indian foods by C. Gopalan, B.V. Rama Sastri and S.C. Balasubramanian , published by National Institute of NutritionIndian Council of Medical Research , Hyderabad.
12. Purnima Dey Sarkar, Lincy K. Skaria, Gopinath Agnihotram. Assessment of nutritional status in Hypothyroid patients. J Pharm Biomed Sci. 2013; 27(27):582-585.
13. Arthur JR, Beckett GJ, 1999 Thyroid function. British Medical Bulletin 55: 658-668.
14. Civitareale D, Saiardi A, Falasca P, 1994 Purification and characterization of thyroid transcription factor 2. Biochem J 304:981-985.
