A Bacteriological Profile of Neonatal Septicemia (Study in tertiary care hospital, Rajkot)
A Bacteriological Profile of Neonatal Septicemia
DOI:
https://doi.org/10.70284/njirm.v4i2.2146Keywords:
Blood culture, Neonatal septicaemia, early onset sepsis, late onset sepsisAbstract
Background: Neonatal septicemia is the major cause of Neonatal mortality. It might be possible to reduce these deaths by early diagnosis and proper management. Objectives: (1) To find out various bacteriological agents involved in neonatal septicaemia in PDU Medical college & Hospital Rajkot (2) to findout the organisms responsible for early onset and late onset neonatal sepsis. Methods: A hospital based prospective study was carried out in 100 clinically supsected cases of neonatal septisemia in New Born Intensive Care Unit (NICU) at P.D.U Medical College & Hospital Rajkot. Results: Out of 100 neonates with clinically suspected neonatal septicemia, 62(62%) were blood culture positive. Gram negative bacteria accounted for 50(80.65%) & Gram positive bacteria accounted for 12(19.35%) of all cases. Among Gram Negative bacteria Klebsiella spp 25(40.32%) being the most common organism & Staphylococcus aureus 8(12.90%) being the most common organism among Gram Positive bacteria. Late sepsis was most commonly associated with klebsiella spp19 (41.3%).Conclusion: Neonatal septicaemia should be diagnosed urgently to reduce the mortality. Suspected infection based on clinical criteria need to supported by microbial investigation to find causative organisms and their antibiotic sensitivity pattern.
References
2. Behrman R, Kleigman R, Nelson Textbook of Pediatrics. 17th Ed 623-638:847-848.
3. Park K. Parks Textbook of Preventive & Social Medicine, 18th Ed 352-404
4. Cloherty J.P.et al, Infections, Manual of Neonatal Care. 4th Ed, 255-340
5. Collee JG, Fraser AG, Marmion BP, Simmons A. Mackie and McCartney Practical Medical Microbiology. 14th ed.
6. Betty A. Forbes, Daniel F. Sahm, Alice S, Weissfeld. Bailey & Scott's Diagnostic Microbiology. 12lh ed,216-247
7. Koneman EW, Allen Stephen D. Colour Atlas and Textbook of diagnostic microbiology. 6th edition
8. Choudhary P, Farel MI, Choudhary M, A Ghapar, Neonatal infection and their outcomes. Indian Pedeatr 1987; 24: 1019-1024.
9. Vinod Kumar CS, Neelagund YF, Kalsunath Suneeta, Banapurmath Sudha et al : Perinatal risk factors and microbial profile of neonatal septicemia. A multicentred study. J. Obst. Gynaec. India, Jan.-Feb. 2008; vol. 58, no. 1 : 32-40.
10. Neelam Kaistha, Manjula Mehta, Nidhi Singla, Ritu Garg, Jagdish Chander J Infect Dev Ctries 2010; 4(1):055-057
11. Bhattacharjee A, Sen MR, Prakash P, Gaur A et al : Brief communication. Increased prevalence of ESBL producer in Neonatal Septicemia cases at a Tertiary Referral Hospital. Ind J. Med. Microbiol, 2008, 26, 4 : 356-360.
12. Khatua SP, Das AK, Chatterjee BD, Ghose B,Saha A, Khatua S : Neonatal Septicemia. Ind. J. Ped 1986; 53 : 509-514.
13. Boo YN, Chor CY et al : Six year trend of neonatal septicemia in large Malaysian hospital. J. Ped. Child Health. Feb 94 : 36.
14. Movahedian AH, Moniri R and Mosayebi Z. Bacterial culture of neonatal Sepsis, Iranian J Publ Health 2006;33:84-89
