Hypertension & Coronary Artery Disease: A Hospital Based Case Control Study

Hypertension & Coronary Artery Disease

Authors

  • Dr. Rohit V Ram
  • Dr. Atul V Trivedi

Keywords:

Case-control study, coronary artery disease, hypertension

Abstract

Background & Objectives: Hypertension is one of the most important modifiable risk factor for coronary artery disease. This study was done to study the role of hypertension in occurrence of coronary artery disease. Methods: Present study was a hospital based paired matched case-control study, carried out at civil hospital, Ahmedabad. 135 newly diagnosed cases of coronary artery disease and 135 controls were studied after taking informed written consent. Data was analysed by using Epi-info version 3.5.1 computer package, Chi -square test, Z test and Odds ratio were calculated. Results: Among the total 135 cases 70.4% were male and 29.6% were female, most of the cases (40%) were belongs to the age group of 51-60 years. Positive family history of hypertension and Coronary Artery Disease were significantly associated with the occurrence of Coronary Artery Disease. Significant association was observed between hypertension and occurrence of Coronary Artery Disease (P<0.001) Conclusion: Hypertension is important etiological factors behind the occurrences of Coronary Artery Disease, but it is modifiable that highlight the need of appropriate control strategies and measures to avert significant proportion of premature morbidity & mortality due to Coronary Artery Disease.

References

1. Reddy KS, Yusuf S. Emerging epidemic of cardiovascular disease in developing countries. Circulation. 1998; 97(6):596-601.
2.Gupta R. Burden of Coronary Heart Disease in India. Indian heart J. 2004; 57:632-638.
3. Prevention of Coronary heart Disease. Tech. Rep. Ser., WHO.1982;678.
4. Pierdomenico SD, Di Nicola M, Esposito AL, Di Mascio R, Ballone E, Lapenna D et al. Prognostic Value of Different Indices of Blood Pressure Variability in Hypertensive Patients. Am J Hypertension. 2009;22(8):842–7.
5. Deepa R, Shanthirani CS, Pradeepa R, Mohan V. Is the ‘rule of haves’ in hypertension still valid? J Assoc Physicians India 2003;51:153-7
6. David G Kleinbaum, Kevin M Sullivan, Nancy D Barker. Active Epi Companion Textbook: A supplement for use with active Epi CD-ROM.
7. Tunstall-Pedoe H, Kuulasmaa K, AmouyelP, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38populations from 21countries in four continents. Circulation 1994;90:583-612
8. Arterial Hypertension.Tech. Rept. Sers., WHO.1978;628.
9. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. JAMA 2003;289: 2560-2571.
10. Sanjay P Zodpey, Hemant R Kulkarni, N. D Vasudeo, S. W Kulkarni. Risk factors for coronary heart disease: A case control study. Indian journal of community medicine.1998;23:7-14.
11. Pinto VG, Motghare DD, Ferreria AMA, Kulkarni MS. Prevalence of coronary heart disease in an urban community of Goa. South Asian Journal of Preventive Cardiology. 2004 Oct-Dec;Vol 8: Number 4.
12. Soumya Deb, Aparajita Dasgupta. A study on risk factors of cardiovascular diseases in an urban health center of Kolkata. Indian J. Commu. Med. 2008;33:271-275.
13. Sangeeta Gulati, AS Sekhon, NK Goel, MK Sharma. A comparative study of risk factors in coronary artery disease in district Patiala. Indian J. Prev.Soc.Med.2004;35:163-167.
14. Prabhakaran D, Shah P, Chaturvedi V, Ramkrishnan L, Manhapara A, reddy KS. Cardiovascular risk factor prevalence among men in a large industry of northen India . Nat Med J India 2005;18:59-65.

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Published

2012-10-31

How to Cite

Ram, D. R. V., & Trivedi, D. A. V. (2012). Hypertension & Coronary Artery Disease: A Hospital Based Case Control Study: Hypertension & Coronary Artery Disease. National Journal of Integrated Research in Medicine, 3(4), 99–102. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/2080

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Original Articles