Clinicobacteriological Study of Pyoderma with Special Reference to Community Acquired Methicillin Resistant Staphylococcus Aureus
Clinicobacteriological Study of Pyoderma
Keywords:
Methicillin Resistant Staphylococcus aureus. (MRSA), Pyoderma, Staphylococcus aureusAbstract
Background: Although prevalence of MRSA strains is reported to be increasing, there are scanty studies of their prevalence in community acquired pyoderma in western India. Aims: This study aimed at determining clinicobacteriological profile & prevalence of Methicillin Resistant Staphylococcus aureus (MRSA) infections in community acquired pyoderma. Materials and methods: Prospective study was carried out in tertiary care hospital in Baroda.100 patients with pyoderma, visiting outpatient department of dermatology, were studied clinically and microbiologically. Sensitivity testing was done for gram positive & gram negative organisms by disc diffusion method. MRSA were detected by Agar dilution method. Result: Primary pyoderma accounts for 64% of cases with highest number of cases were of Impetigo (26%). The culture positive rate was 83% with Staphylococcus aureus being the major pathogen. (78.82%) Out of these 10.45% strains of Staphylococcus aureus were Methicillin Resistant Staphylococcus aureus. (MRSA) Conclusion: MRSA as a cause of pyoderma is a reality albeit in present study group. All the MRSA isolated were sensitive to Vancomycin. Sensitivity to Amoxyclav, Fluoroquinolones & Macrolides is quite good, which can be used for treatment.
References
2. T.V. Ramani, P.A. Jayakar. Bacteriological study of 100 cases of pyoderma with special reference to Staphylococci, their antibiotic sensitivity and phage pattern. Indian J. Dermatol Venereol Lepr 1980; 46(5): 282-286.
3. Tan Hiok Hee. A study of bacterial skin infection in NSC. NSC Bulletin for Medical Practitioners 1996; 7(2).
4. Ayyagary A. Agarwal HC, Kaur S. et al. Prevalence of Corynebacterium diptheriae in pyoderma andother skin lesions. Indian J Pathol Microbiol 1979; 22: 37-45.
5. Ghadage DP, Sali YA. Bacteriological study of pyoderma with special reference to antibiotic susceptibility to newer antibiotics Indian J Dermatol Venereol Lepr 1999; 65(4): 177-181.
6. Itzhak Brook. Secondary bacterial infections complicating skin lesions J. Med. Microbiol 2002; 51: 808-812.
7. Mark D. King, Bianca J. Humphrey, Yun F. Wang et al. Emergence of community acquired methicillin - resistant Staphylococcus aureus USA 300 Clone as the predominant cause of skin and soft-tissue infections. Annals of internal medicine 2006; 144: 309-317.
8. Rahul Patil, Sujata Bavea, Gita Natraj et al. Prevalence of methicillin - resistant Staphylococcus aureus (MRSA) in community acquired primary pyoderma. Indian J Dermatol Venereol Leprol 2006; 72(2): 126-128.
9. Community - Associated MRSA Information for clinicians [CDC web site] February3,2005Availableat:http://www.cdc.gov/ncidod/dhqp/ar_mrsa_ca_clinicians.html. Accessed December 5, 2006.
10. J. Gerald Colle, Andrew G. Frascr, Barrie P. Marmion et al. Mackie & McCartney Practical Medical Microbiology, 14th edition London: Churchill Livingstone; 1999.
11. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial disc susceptibility test, 7th edition. Approved standards, NCCLS Document M2-A7, Vol. 20(1); Wayne, PA 2000.
12. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 5th edition. Approved standards, NCCLS Document M-7A5, Wayne, PA 2000.
13. Ahmed Khalil, Batra Asheesh, Roy Renu et al. Clinical & bacteriological study of pyoderma in Jodhpur-western Rajasthan. Indian J Dermatol Venereol Lepr 1998; 64(3): 156-157.
14. R.G. Baslas, S.K. Arora, R.D. Makhija et al. Organism causing pyoderma and their susceptibility patterns. Indian J Dermatol Venereol Lepr 1990; 56: 127-129.
15. K.C. Kandhari, Om Prakash, and Gurmohan Singh. Bacteriology of pyodermas. Indian Journal
of Dermatology and Venereology 1962; 28: 125-133.
16. Nissim Ohana, Joram Keness, Ehud Verner et al. Skin - isolated community - acquired Staphylococcus aureus: In vitro resistance to methicillin and erythromycin. Journal of American Academy of Dermatology 1989; 21(3): 544-546.
17. Maria W. Sugeng, Por Ang, Hiok Hee Tan et al. Characteristics of bacterial skin infection in children compared to adults at a tertiary dermatologic center. International Journal of Dermatology 199; 38: 582-586.
18. Sonal Sexana, Kavita Singh and Vibha Talwar. Methicillin - resistant Staphylococcus aureus prevalence in community in the East Delhi area. Jpn. J. Infect. Disease 2003; 56: 54-56.
