Usefulness of Fine Needle Aspiration Cytology in Diagnosis of Neck Masses
Usefulness of FNAC
DOI:
https://doi.org/10.70284/njirm.v2i4.1935Keywords:
Fine Needle Aspiration Cytology, Neck Mass, sensitivity, specificityAbstract
Background: Fine needle aspiration cytology (FNAC) is a well established, simple, quick, inexpensive and minimally invasive diagnostic technique. Neck region of human body is relatively small area but houses a fairly large number of organs with a variety of lesions and consequently require from conservative to aggressive management protocols. Aims and objectives: To assess sensitivity and specificity or diagnostic value of FNAC of neck masses keeping histopathology as gold standard. Materials and Methods: Surgical biopsies or excisions from neck masses were received in fifty nine cases in which prior FNAC was done. The findings of histopathological study were correlated with the diagnosis given on FNAC. Further the sensitivity and specificity were calculated. Results: Twenty eight aspirates were from lymph nodes, fourteen were from thyroid gland, thirteen were of salivary gland origin and four were others. Out of the Fifty nine cases the diagnosis of forty four (74.57%) was corroborated by histopathology. In fifteen (25.42%) cases the histopathological diagnosis was dissimilar to that of FNAC. The overall sensitivity of FNAC in the diagnosis of neck masses was calculated to be 83.01% and specificity was 78.94%. Sensitivity was highest (82.14%) for neck lymph nodes and lowest for thyroid masses (64.28%). Specificity was the highest for other neck masses (100%) and the lowest for neck nodes (71.2%). Conclusion: FNAC of neck masses is an effective diagnostic tool but its sensitivity and specificity of diagnosis in different organs should be kept in mind while creating a management protocol for the patient.
References
2. Wenig BM, Cohen J-M. General principles of head and neck pathology. In Harrison LB, Sessions RB, Hong WK editors. Head and Neck Cancer A multidisciplinary approach. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, a Wolters Kluwer business; 2009.p.11-12.
3. Watkinson JC, Wilson JA, Gaze M, Stell PM, Maran AGD. Stell and Maran’s Head and neck surgery, Butterworth-Heinemann, Oxford, 4th edition, chapter 2; 2000. p 20-21.
4. Tilak V, Dhaded AV, Jain R. Fine needle aspiration cytology of head and neck masses. Indian J Pathol Microbiol. 2002 Jan; 45(1):23-9.
5. Howlett DC, Harper B, Quante M, Berresford A, Morley M, Grant J, Ramesar K, Barnes S. Diagnostic adequacy and accuracy of fine needle aspiration cytology in neck lump assessment: results from a regional cancer network over a one year period. J Laryngol Otol. 2007 Jun; 121(6):571-9.
6. Schwarz R, Chan NH, MacFarlane JK. Fine needle aspiration cytology in the evaluation of head and neck masses. Am J Surg. 1990; 159(5): 482-5.
7. Schelkun PM, Grundy WG. Fine-needle aspiration biopsy of head and neck lesions.
J Oral Maxillofac Surg. 1991; 49(3): 262-7.
8. Layfield LJ. Fine-needle aspiration of the head and neck. Pathology (Phila).1996; 4(2): 409-38.
9. Tandon S, Shahab R, Benton JI, Ghosh SK, Sheard J, Jones TM. Fine-needle aspiration cytology in a regional head and neck cancer center: comparison with a systematic review and meta-analysis. Head Neck. 2008; 30 (9):1246-52.
10. Amedee RG, Dhurandhar NR. Fine-needle aspiration biopsy. Laryngoscope.2001; 111(9):1551-7