Study of Hematological Parameters In Dengue Fever: A Retrospective Study
Study of Hematological Parameters In Dengue Fever: A Retrospective Study
Keywords:
Dengue, endemic, leucopenia, thrombocytopenia, dengue shock syndromeAbstract
Background and objectives: Dengue is a major preventable and treatable cause of morbidity and mortality among children and adults. Hematological examination is an essential step in the management. Hence this study was undertaken to document the haematological changes in dengue fever. Method: This is a retrospective study conducted in the Department of Pathology for a period of 6 months from January to June 2016. All patients with fever and clinical suspicion of dengue were subjected to NS1 antigen test. Patients with documented NS1 positivity were included in the study. Hematological analysis was done by 5 part differential cell counter and subsequent peripheral smear examination. Results: Total 57 serologically positive dengue cases were seen during the study period. Maximum no of cases were seen in January-February. Range of haemoglobin percentage was lowest 4.2 g/dl and highest 15.6 g/dl with a mean of 11.95g/dl. 50.8% had platelets above 75000 while 5.3% had <20000/cu mm. 52.6% had normal leucocytic count, 35% had leucopenia and 12.3% had leucocytosis. Conclusion: Dengue infection is on a rise in india. Many experts believe that it is now endemic in india and no longer seasonal since a cases can be detected round the year though the peak incidence still remains during the rains. Any patient with fever and other clinical symptoms suspicious of dengue should be subjected to complete haematological profile as well as specific tests for dengue. Early and prompt diagnosis goes hand in hand with aggressive measures for proper sanitation can greatly limit dengue afflicted mortality. [Madhuri K NJIRM 2017; 8(4):58-62]
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