Study of Risk Factors for Pregnancy Induced Hypertension (A Hospital Based Case Control Study)

Study of Risk Factors for Pregnancy Induced Hypertension

Authors

  • Sorohi Hirpara
  • Rushi Ghevariya
  • Paras Ghadia
  • Trupesh Hada
  • Niraj Pandit

Keywords:

PIH, case-control study, vegetarian diet, previous PIH, hospital study

Abstract

Hypertension disorders of pregnancy are important leading causes of maternal, fetal and neonatal morbidity and mortality worldwide. Hypertension during pregnancy is classified under five categories; they are chronic hypertension, preeclampsia, chronic hypertension with preeclampsia, gestational hypertension (Pregnancy Induced Hypertension-PIH) and transient hypertension. The present study was initiated as undergraduate student study to determine the risks factors of pregnancy induced hypertension. Method: The present case-control study was conducted during July 2016 to Oct 2016 at tertiary care hospital. The study population is selected from the hospital OPD. There were total 100 pregnant women selected for the study. There were selected on first come first basis. There were 50 women with PIH and 50 women without PIH selected for the study. The cases were selected from list of Obstetric OPD and matched control were also selected form same department. The socio-demographic matched case and control selected in equal number 1 : 1 ratio. Results: The women with PIH and without PIH, both groups were matched for their background information. It was found that there was no association with primipara and multipara with PIH (Odds – 1.7 95% CI – 0.68 to 4.30). Menstrual history had also no association with present PIH condition (OR- 0.5 95% CI- 0.2 to 1.6 ). Family history of hypertension (OR-1.9 95% CI- 0.8 to 4.8) and family history of diabetes mellitus (OR-1.5 95% CI- 0.61 to 3.7) also had not association with present PIH. Past history of PIH had strong association with current PIH for women who are multigravida (OR-3.7 95% CI- 1.1 to 12.5 p=0.03). Also there was interesting observation that vegetarian had higher chance of getting PIH then mixed diet pattern (OR-4.3 95% CI- 1.8 to 10.4 p=0.0009). Conclusion: The various risk factors were studies among PIH women and non-PIH women as case control study. The risk factors which present study have identified, they were past history of PIH and vegetarian diet. Others need to explore in larger community based study. [Sorohi H NJIRM 2017; 8(3):49-52]

References

1. World Health Organization, 2011 WHO Recommendations for prevention and treatment of pre-eclampsia and eclampsia. Data [Internet]. [cited 2017 Jan 20]. Available from: http://apps.who.int/iris/bitstream/10665/44703/1/9789241548335_eng.pdf
2. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertens Dallas Tex 1979. 2003 Dec;42(6):1206–52.
3. Kintiraki E, Papakatsika S, Kotronis G, Goulis DG, Kotsis V. Pregnancy-Induced hypertension. Horm Athens Greece. 2015 Jun;14(2):211–23.
4. You F, Huo K, Wang R, et al, 2012 Maternal mortality in Henan Province, China: changes between 1996 and 2009. PLoS One 7.
5. Rahman LA, Hairi NN, Salleh N. Association between pregnancy induced hypertension and low birth weight; a population based case-control study. Asia Pac J Public Health. 2008;20(2):152–8.
6. Maternal mortality ratio (modeled estimate, per 100,000 live births) | Data [Internet]. [cited 2017 Jan 20]. Available from: http://data.worldbank.org/indicator/SH.STA.MMRT?locations=IN
7. DC Dutta’s Textbook of Obstetrics, Konar Hiralal 2013 edition; Calcutta National Medical College and CR Hospital, Kolkat.
8. Prakash J, Pandey LK, Singh AK, Kar B. Hypertension in pregnancy: hospital based study. J Assoc Physicians India. 2006 Apr;54:273–8.
9. Bangal VB, Giri PA, Mahajan AS. Maternal and foetal outcome in pregnancy induced hypertension : a study from rural tertiary care teaching hospital in India. Int J Biomed Res. 2012 Jan 1;2(12):595–9.
10. Tebeu PM, Foumane P, Mbu R, Fosso G, Biyaga PT, Fomulu JN. Risk factors for hypertensive disorders in pregnancy: a report from the maroua regional hospital, cameroon. J Reprod Infertil. 2011 Jul;12(3):227–34.
11. K R, Gandhi S, Rao V. Socio-demographic and other risk factors of pre eclampsia at a tertiary care hospital, karnataka: case control study. J Clin Diagn Res JCDR. 2014 Sep;8(9):JC01-04.
12. Kaur L, Puri M, Kaushik S, Sachdeva MP, Trivedi SS, Saraswathy KN. Genetic thromobophilia in pregnancy: a case-control study among North Indian women. J Thromb Thrombolysis. 2013 Feb;35(2):250–6.
13. Qiu C, Williams MA, Leisenring WM, Sorensen TK, Frederick IO, Dempsey JC, et al. Family history of hypertension and type 2 diabetes in relation to preeclampsia risk. Hypertens Dallas Tex 1979. 2003 Mar;41(3):408–13.
14. Abetew DF, Enquobahrie DA, Dishi M, Rudra CB, Miller RS, Williams MA. Age at menarche, menstrual characteristics, and risk of preeclampsia. ISRN Obstet Gynecol. 2011;2011:472083.

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Published

2018-02-02

How to Cite

Hirpara, S., Ghevariya, R., Ghadia, P., Hada, T., & Pandit, N. (2018). Study of Risk Factors for Pregnancy Induced Hypertension (A Hospital Based Case Control Study): Study of Risk Factors for Pregnancy Induced Hypertension. National Journal of Integrated Research in Medicine, 8(3), 49–52. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/1243

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Original Articles