Comparison of Intrathecal Adjuvants with Bupivacaine Using Fentanyl 50ïg and Butorphanol 25ïg
Comparison of Intrathecal Adjuvants with Bupivacaine Using Fentanyl 50 ug and Butorphanol 25 ug
Keywords:
Analgesia, anesthesia, bupivacaine, Butorphanol, Fentanyl, spinalAbstract
Background and objectives: Spinal opiates potentiate the effect of local anesthetic agent providing longer lasting post-operative analgesia. We compared injection butorphanol and Fentanyl as an adjuvant to Bupivacaine with respect to onset, duration of sensory and motor block and duration of analgesia. Method: Study was carried out on 60 patients aged between 18-55yrs of ASA grade I and II, 30 in each group under spinal anaesthesia. An adjuvant Injection of Butorphanol 25 g (Group-B) and fentanyl 50 g (Group-F) were added to Inj Bupivacaine 15 mg(0.5%). Onset of sensory and motor blockade, extent of analgesia and occurrence of any complications were studied in both groups. All patients were also observed for analgesia by VAS pain score post-operatively. Results: There was no significant difference in the onset of sensory and motor blockade in both the groups.The pulse rate in group butorphanol was 72.9 9.41 per min and fentanyl group 86.066.58 per min from 45-90 min after the subarachnoid block was given which was significantly lower. Duration of sensory block was 230.624.7 min and 197.815.4 min and the duration of motor block was 24632.6 min and18016.8min and post-operative analgesia was 303.640.4min and 269.415.4min in group Butorphanol and Group Fentanyl respectively which were significantly higher in gp Butorphanol. Conclusions: Adjuvance of 25g Butorphanol to intrathecal Bupivacaine significantly prolongs sensory and motor block as well as post-operative analgesia when compared to adjuvant 25g Fentanyl providing effective anesthesia for surgeries taken under spinal anesthesia. [Upasna B NJIRM 2017; 8(3):41-48]
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