A Four Year Study Of Vibrio Cholerae Isolates At A Tertiary Care Centre
A Four Year Study Of Vibrio Cholerae Isolates At A Tertiary Care Centre
Keywords:
Vibrio cholerae, El Tor, O1 Ogawa, MICAbstract
Background and objective: Cholera is an acute diarrhoeal disease caused by Vibrio cholerae. Cholera continues to be a major concern for the developing countries as it is an important cause of morbidity and mortality. Vibrio cholerae O1 El Tor Ogawa has been the offending agent since 1964. The present study was undertaken to determine prevalence, distribution of biotypes, serotypes, antibiotic susceptibility pattern of Vibrio cholerae and their MIC to tetracycline. Methods: Stool samples from suspected cases of cholera admitted were received in the laboratory for culture and sensitivity testing. The culture of specimens, identification and biochemical characterization of isolates were done as per standard techniques. Results: During the study period a total 450 stool samples were processed and 69 (15.33%) V.cholerae were isolated from them. All were El Tor O1 Ogawa. MIC of isolates also increased significantly during the study period. Interpretation and conclusion: Cholera is an acute type of diarrheal illness that affected millions of people around the world over the centuries. All the isolates (15.33%) were V.cholerae El Tor O1 Ogawa. Maximum isolation was in 2014 (36.23%). Resistance to tetracycline has increased from 6.25% in 2012 to 80% in 2015. Similarly resistance to ampicillin and cotrimoxazole has also increased substantially. Improved surveillance is useful in assessing the actual burden of cholera and in planning interventions. Increasing resistance pattern of V.cholerae is a matter of concern. [Kirti G NJIRM 2017; 8(1): 38-40]
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