An Open, Retrospective Study Of Comparison Of Fine Needle Aspiration Cytology (FNAC) And Histopathology Findings In 75 Cases Of Solitary Thyroid Nodule.
Comparative Study of FNAC and Histopathology of Thyroid Nodule
Keywords:
solitary thyroid nodule (STN), fine needle aspiration cytology (FNAC), histopathology examination (HPE)Abstract
Background and objectives: Solitary thyroid nodule(STN} is a common clinical entity encountered in routine clinical practice.STN is defined as a single swelling involving either lobe of thyroid or isthmus of thyroid gland. Present study was undertaken to know distribution of lesion according to age and sex, and also to evaluate efficacy of FNAC in diagnosis of clinically obvious and palpable solitary thyroid nodule. Method: This study was done on 75cases operated in our hospital from May 2012 to May 2016. All patients included in the study were submitted to FNAC and ultrasonography. All patients were subjected to surgery and histopathology examination was obtained. Results: Out of 75 cases of thyroid lesions, 63 cases were benign (84%), 6 cases were malignant (8%) and 6 cases were suspicious(8%) on FNAC. On Histopathological examination, 60 cases were benign(80%) and 15 cases were malignant(20%). Conclusion: FNAC is a single best investigation for preoperative evaluation for STN to differentiate between benign and malignant nodules with 88% accuracy rate.[Doshi H NJIRM2016; 7(5):53-55]
References
2. TunbridgeWM : The spectrum of thyroid disease in a community. TheWichmansurvey.clin endocrineno1997;17:481-493
3. D.N.poller,E.B. stelow and C.yiangou. Thyroid FNAC cytology:can we do it better? J cytopathology;2007;DOI:10.1111
4. Miller JM, kini SR, HambergJI. The needle biopsy diagnosis of papillary thyroid carcinoma. Cancer 1985;55:2812-2817
5. Manoj Gupta, Savitagupta and Vedbhushangupta. Correlation of fine needle aspiration cytology with histopathology in diagnosis of solitary thyroid nodule. Journal of thyroid research, Vol.2010;Article ID379051;5 pages
6. H.A. Nggada, A.B.musa, B.M.Gali&M.I.Khalil: FNAC of thyroid nodule(s): A Nigerian tertiary hospital experience. The internet journal of pathology.2006 volume 5 Number 1.
7. Vander JB, Gaston EA, Dawber TR: The significance of non toxic thyroid nodule. Ann Intern Med 1982;96:221-232
8. Hoffman HW: Diagnosis accuracy of fine needle aspiration biopsy in the diagnosis of thyroid malignancy. Pathologist 1986;9:9-14
9. Aschcraft MW, Van Herle AJ: Management of thyroid nodules II. Scanning techniques, thyroid suppression therapy and fine needle aspiration. Head and neck surg1981;3:297-322
10. Hoffman GL et al: The solitary thyroid nodule. Arch. Surg.105,319-384
11. Willems JS, Lowhagen T: The role of FNAC in the management of thyroid disease.ClinEndocinolMetabol 1981;10:267-273
12. M.M.Kapur: Solitory thyroid nodule. Indian Journal of Surgery, March 1982,174-179
