Study Of Bacteriological And Antimicrobial Susceptibility Pattern Of Uropathogens

Study Of Bacteriological And Antimicrobial Susceptibility Pattern Of Uropathogens

Authors

  • Dr Roshni Patel
  • Dr Falguni Chavada

Keywords:

Antimicrobial susceptibility pattern, Bacteriological pattern, Urinary tract infection

Abstract

Background & Objective: Urinary tract infection is one of the common infections in the Indian community. Distribution and susceptibility of UTI-causing pathogens change according to time and place. This study aims to analysis present trend of locally prevalent uropathogens and their antibiotic susceptibility for prudent use of antibiotics to combat antimicrobial resistance. Methodology: Total 135 urine samples from suspected UTI was collected from both outdoor and indoor patients during the study period of August 2014 to Jun 2015.Culture and antibiotic sensitivity testing of the isolates were done. At the last, analysis of uropathogen and antibiotic susceptibility pattern was done. Results: Total 54(40%) samples were found to be positive for uropathogen in culture, in which gram negative organisms & gram positive organisms were isolated from 45 (83%) & 9(17%) samples, respectively. The E coli was most common organism isolated. Conclusion: Females are predominantly affected by UTI, with most common uropathogen E coli. Antimicrobial susceptibility pattern shows high sensitivity for Amikacin and levofloxacin compared to other routinely used antibiotics. [Patel R NJIRM 2016; 7(1):47-49]

References

1. Ronald AR, Nicolle AE, Stamm E, et al. Urinary tract infection in Adults: Research priorities and strategies. Int J Antimicrob Agents.2001;17:343-348.
2. Morgan MG, McKenzie H. Controversies in the laboratory diagnosis of community-acquired urinary tract infection. Eur J Clin Microbiol Infect Dis. 1993; 12:491-504.
3. Zarb P, Coignard B, Griskevicienne J et al. The European Centre for Disease Prevention and Control (ECDC) pilot point prevalence survey of healthcare-associated infections and antimicrobial use.Euro Surveill 2012, 17(46):pil=20316.
4. Magill SS, Edwards JR, Bamberg W et al. Multistate point-prevalence survey of health care-associated infections.N Engl J Med 2014, 370:1198-1208.
5. Gupta K, Scholes D, Stamm WE. Increasing prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in women. J Am Med Assoc. 1999;281:736–738.
6. Gupta K, Sahm DF, Mayfield D, Stamm WE. Antimicrobial resistance among uropathogens that cause community-acquired urinary tract infections in women: a nationwide analysis. Clin Infect Dis. 2001;33:89–94.
7. Cassier P, Lallechère S, Aho S, et al. Cephalosporin and fluoroquinolone combination are highly associated with CTX-M β-lactamase-producing Escherichia coli: a case control study in a French teaching hospital. Clin Microbiol Infect 2011;17(11):1746-51.
8. Manges AR, Natarajan P, Solberg OD, et al.The changing prevalence of drug-resistant Escherichia coli clonal groups in a community: evidence for community outbreaks of urinary tract infections.Epidemiol Infect. 2006;134:425–31.
9. Kahan NR, Chinitz DP, Waitman DA, et al. Empiric treatment of uncomplicated urinary tract infection with fluoroquinolones in older women in Israel: another lost treatment option? Ann Pharmacother. 2006;40:2223–7. 10. M.Grabe,R Bartoletti et al.Bacterial resistance developmsent. Guidelines on urological infections. 2014: 8
11. Ritu Aggarawal,Maneesh Goyal et al. Bacterial isolates and their antibiotic susceptibility profile recovered from urine samples in NCR,Ghaziabad(U.P) JEMDS 2014;3(28):7831-7836.
12. Nirajkumas Biswas,Parimal H Patel et al. Bacteriological profile of urinary tract infection and its antibiotic susceptibility at tertiary care hospital ,Valsad,Gujarat,India . J Pharm Biomed Sci. 2014;04(09):751-754.
13. Devanand Prakash,Ramchandra Sahai Saxena Distribution and Antimicrobial Susceptibility Pattern of Bacterial Pathogens Causing Urinary Tract Infection in Urban Community of Meerut City, India.ISRN Microbiology.Volume 2013
14. N. Suneetha*,P. Subbulu, S. Usha Vidya Rani, et al. Bacteriological Study of Urinary Tract Infection. IJIMS, 2015, 2(4), 11-16.
15. M. Eshwarappa, R. Dosegowda, I. Vrithmani Aprameya,et al. Clinico-microbiological profile of urinary tract infection in south India .Indian J Nephrol. 2011 Jan-Mar; 21(1): 30–36.
16. Bashir MF,Qazi JI, Ahmad N Riaz S .Diversity of urinary tract pathogens and drug resistant isolates of Escherichia coli in different age and gender groups of Pakistanis . Tropical Journal of Pharmaceutical Research, September 2008; 7(3): 1025-1031
17. Getenet B,Wondewosen T. Bacterial uropathogens in Urinary tract infections and Antibiotic susceptibility pattern in JIMMA university specialized hospital ,Southwest Ethiopia .Ethiop J Health sci .vol .21 ,No.2 JULY 2001 (2):141-456.
18. BL Chaudhary,Charu Chandra & Snehanshu Shukla.Bacteriology of urinary tract infection & antibiotic susceptibility pattern among diabetic patients.International journal of Bioassay.2014,3(08),3224-3227.
19. R. N. Das, T. S. Chandrashekhar, H. S. Joshi, Frequency and susceptibility profile of pathogens causing urinary tract infections at a tertiary care hospital in western Nepal.Singapore Medical Journal, 2006; 47(4): 281–285

Downloads

Published

2018-01-18

How to Cite

Patel, D. R., & Chavada, D. F. (2018). Study Of Bacteriological And Antimicrobial Susceptibility Pattern Of Uropathogens: Study Of Bacteriological And Antimicrobial Susceptibility Pattern Of Uropathogens. National Journal of Integrated Research in Medicine, 7(1), 47–49. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/1043

Issue

Section

Original Articles

Most read articles by the same author(s)