Type 2 DM An Independent Risk Factor For Poor Outcome In Moderate To Severe COVID-19

Type 2 DM An Independent Risk Factor For Poor Outcome In Moderate To Severe COVID-19

Authors

  • Dr. Sona Mitra Clinical Research Associate,Parul University, Waghodia, Vadodara, Gujarat, India
  • Dr. Arti Muley Professor,Department Of Medicine,Parul University, Waghodia, Vadodara, Gujarat, India
  • Dr. Ashish Bavishi Infectious Disease Specialist,Department Of Medicine,Parul University, Waghodia, Vadodara, Gujarat, India
  • Dr. Hema Bhojani Assistant Professor,Department Of Medicine,Parul University, Waghodia, Vadodara, Gujarat, India
  • Dr. Dinesh Nakum Senior Resident,Department Of Medicine,Parul University, Waghodia, Vadodara, Gujarat, India
  • Dr. Vidhi Parikh Intern, Department Of Medicine,Parul University, Waghodia, Vadodara, Gujarat, India
  • Dr. Shivani More Intern, Department Of Medicine,Parul University, Waghodia, Vadodara, Gujarat, India
  • Dr. Vrunda Mehta MPH Scholar, PIMSR, Parul University, Waghodia, Vadodara, Gujarat, India

DOI:

https://doi.org/10.70284/njirm.v13i2.3448

Keywords:

COVID-19, Diabetes Mellitus, Severity, Mortality

Abstract

Background: Diabetes Mellitus has been shown to be a risk factor for severe COVID-19 disease. Few studies assessed effect of diabetes on the outcome exclusively in moderate to severe COVID 19 disease. Objective: To compare the clinical characteristics and outcome of hospitalized moderate and severe COVID-19 disease among patients with and without diabetes. Material And Methods: This retrospective study was conducted at Parul Sevashram Hospital from 1st April 2021- 30th April 2021. Data on demographic profile, clinical symptoms, laboratory findings, complications and clinical outcome was collected and compared between patients with and without diabetes. Result: Total 319 patients were included with mean age 54.81±11.72 years. 28.5% had diabetes. The most common symptoms were fever, cough and shortness of breath. As compared to patients without diabetes, these patients had significantly higher levels of leucocyte count, CRP, Ferritin, LDH and D-Dimer. They also had more complications like ARDS, secondary infection and stroke and higher need of respiratory support (92.3% vs. 69.7%, P < 0.001). We also observed significantly greater mortality in patients with diabetes compared to those without diabetes (29.7% vs. 13.6%; P = 0.0014). These findings held true even on comparing patients with only diabetes as comorbidity to those without any comorbidity. Conclusion: The study confirms that diabetes is an independent risk factor for higher inflammatory markers, risk of complications and in hospital mortality during hospitalization with moderate to severe COVID 19. New strategies are needed for more aggressive management of COVID 19 cases with diabetes to improve prognosis in these cases. [Mitra S Natl J Integr Res Med, 2022; 13(2): 11-19, Published on Dated: 10/02/2022]

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Published

2022-02-10

How to Cite

Dr. Sona Mitra, Dr. Arti Muley, Dr. Ashish Bavishi, Dr. Hema Bhojani, Dr. Dinesh Nakum, Dr. Vidhi Parikh, Dr. Shivani More, & Dr. Vrunda Mehta. (2022). Type 2 DM An Independent Risk Factor For Poor Outcome In Moderate To Severe COVID-19: Type 2 DM An Independent Risk Factor For Poor Outcome In Moderate To Severe COVID-19. National Journal of Integrated Research in Medicine, 13(2), 11–19. https://doi.org/10.70284/njirm.v13i2.3448

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