Comparison Of Maternal And Fetal Outcome Following Caesarean Section In Pre- Eclamptic Patients Under General And Spinal Anesthesia

Abstract

Background: Pre-eclampsia is a multi-system disorder in pregnancy associated with significant maternal morbidity and mortality and also affects neonatal outcome. Choice of anesthesia technique and skillful management is equally important for maternal and fetal well-being. So, this study was designed to compare the maternal and fetal outcome following cesarean section in pre-eclamptic patients under general and spinal anesthesia. Material And Methods: This prospective, randomized observational study was carried out in 60 parturients age between 18 to 40 years divided in two groups 30 parturients in each. ASA Physical Status II and III who delivered after 34 weeks of gestation with criteria of mild pre-eclampsia by means of Elective/emergency C-section were included. After giving pre medication Group G received thiopentone, succinylcholine intravenously before intubation followed by oxygen, sevoflurane and atracurium (after delivery of baby). Group S received spinal anesthesia by using 2 ml of 0.5% heavy bupivacaine. Heart rate, blood pressure, SpO2 of mother and neonate were recorded at specific time points. Also post of ICU shifting of mother for maternal outcome and APGAR score at 1,5,7 minutes, ABGA, resuscitation requirement and NICU admission data were recorded for fetal outcome. Result: After induction maternal heart rate and blood pressure were higher side (still within 30% from baseline) in group G as compared to group S. APGAR score, ABGA and NICU shifting requirements had favorable outcome in group S. Conclusion: Spinal anesthesia is first choice as it is more safe, simple and with better maternal and fetal outcome. [Vaghasia A Natl J Integr Res Med, 2021; 12(6): 68-80]