A Comparative Study Of Cardiovascular Autonomic Function Test In Diabetes Mellitus Subjects And Controls

Comparative Study of Cardiovascular Autonomic Function Test In Diabetes Mellitus

Abstract

Background: Autonomic neuropathy is the most common complication of diabetes, whose severity is related to duration of diabetes and the degree of the metabolic control. The degree of loss of autonomic functions can be assess by series of autonomic tests. The aim of the present study was to find out the effects of diabetes mellitus on autonomic functions and the sensitivity of sympathetic tests in the early detection of autonomic dysfunction in Type 2 diabetics. Material and Methods: In this cross sectional study, 30 diabetics subjects were compared with 30 non-diabetics controls (plasma glucose level between 80-120 mg %) for their autonomic functions. Each subject was evaluated for cardiovascular autonomic neuropathy by isometric hand grip test & Blood pressure response to standing. Statistical analysis was performed using t test. Result: In Sustain hand grip test the mean difference in diastolic blood pressure was statistically significant p<0.01 &Lying to standing blood pressure test has shown significantly altered autonomic functions amongst diabetics than non-diabetics. Conclusion: Diabetes mellitus is one of the systemic disease which leads to autonomic dysfunctions when compared to non-diabetes which may be because of increased blood glucose. [Selot B Natl J Integr Res Med, 2020; 11(3):19-22]