Correlation Of Hematological And Radiological Parameters With Functional Outcome In Patients Of Acute Ischemic Stroke

Hematological And Radiological Parameters With Functional Outcome In Patients Of Acute Ischemic Stroke

Abstract

Background: Stroke in developing countries is reported to have a younger mean age at onset as compared to developed countries. Objectives: To correlate hematological and radiological parameters with functional outcome in patients of acute ischemic stroke. Material & Methods: This study was undertaken in the Department of Medicine in collaboration with the Departments of Radio diagnosis and Pathology, Jawahar Lal Nehru Medical College and Hospital, AMU, Aligarh from January 2017 to November 2018. By convenience method for sampling, 102 patients who were admitted with the diagnosis of acute ischemic stroke to IPD of JNMCH, Aligarh, on clinical as well as radiological grounds were taken into study. Results: There was a positive correlation between serum cortisol and functional outcome according to m RS. As serum cortisol increased, m RS grade also increased with a correlation coefficient of 0.812 and the result was statistically significant (p <0.01). There was a negative correlation between serum albumin and functional outcome according to m RS. As serum albumin increased, m RS grade decreased with a correlation coefficient of -0.659 and the result was statistically significant (p <0.01). There was no correlation between CCA-IMT and functional outcome (r=0.091) and neither was the result statistically significant. Conclusion: Serum cortisol level was found to have a significant positive correlation with radiological parameter and worsening functional outcome. Serum albumin was found to have a neuroprotective effect. [Saman F Natl J Integr Res Med, 2020; 11(3):1-6]