FFR Guided Coronary Intervention In Intermediate Coronary Artery Disease: Acute and Intermediate Term Results

FFR Guided Coronary Intervention In Intermediate Coronary Artery Disease

Abstract

Background: Fractional Flow Reserve (FFR), a diagnostic test, is a physiological test to determine the functional significance of any stenosis in coronary artery. It is a pressure-derived ratio that estimates blood flow through a stenotic lesion at maximal hyperemia. FFR is objective measurement of stenosis in comparison to traditional visual interpretation of angiography. The objective of this study was to plan the treatment course of patients on the basis of FFR estimation in intermediate coronary artery disease and follow them up for the acute and intermediate term results. Material and Method: The study was performed on suitable identified patients of VS general Hospital, Ahmedabad. First, the diagnostic angiography was done. If angiography result showed intermediate lesion, FFR was measured with sensor wire and decision of management of the patient was taken according to the result of FFR. The results were compared with the results of management of patients by conventional angiography guidance. Results: When management of the patient was based on FFR result, event free survival rate was better with less number of major adverse cardiovascular events than traditional way of patient management based on angiography alone. Conclusion: It could be concluded that the addition of coronary physiological measurements like FFR complements traditional angiographic information and is essential for accurate clinical decision-making. It is cost-effective and prevents unnecessary Per-cutaneous Coronary Intervention (PCI). [Patel K Natl J Integr Res Med, 2020; 11(2):11-16]