Assessment Of Serum Cholesterol Ratio To Know The Risk Of Development Of Cardiovascular Disease In Smokers.

Abstract

Introduction: Smoking in different forms is a major risk factor for atherosclerosis and coronary heart disease. Smoking leads to increase in concentration of serum total cholesterol, low density lipoprotein. It leads to alteration in physiological factors which includes altered coagulation state, damaged vascular wall and alteration in lipid and lipoprotein content.  Total cholesterol/HDL ratio is a simple investigation which helps to estimate future cardiovascular morbidity and mortality among smokers. Material And Method : The present study was conducted on 50 healthy male smokers selected from staff, volunteers and patients attending the hospital OPD. Serum cholesterol and serum HDL was measured. Ratio of total cholesterol/HDL was assessed. The statistical analysis was done by computer programs using Microsoft Excel. Result:The total cholesterol/HDL ratio helps to assess the risk of development of cardiovascular disease. The result shows that smoking influences the ratio of lipid profile adversely causing dyslipidaemia in smokers. More than 50% of smokers have average risk of developing cardiovascular disease. Conclusion: Total cholesterol/HDL ratio is a good indicator for the risk assessment of cardiovascular disease. Early detection of risk level helps to take prophylactic steps like cessation of smoking, change in life style, exercise etc [Joshi N NJIRM 2018; 9(1): 136-137]