Assessment Of Common Carotid Artery Hemodynamic Parameters To Evaluate Risk Factor Smoking For Development Of Cerebrovascular Stroke By Using Carotid Doppler Ultrasound.

Assessment Of Common Carotid Artery Hemodynamic Parameters

Abstract

Abstract: Background : Globally, smoking is considered to be associated with several public health problems including stroke . Common carotid artery (CCA) hemodynamic parameters peak systolic velocity (PSV), end diastolic velocity(EDV) and resistive Index(RI) have an association with the development of stroke. Material Method: The present study was conducted on 16 smokers with Stroke (Group A) and 22 hypertension with diabetic smokers non stroke patients (Group B) . CCA peak systolic velocity, end diastolic velocity and resistive Index were assessed in each group by Doppler ultrasound machine. BMI and W/H was measured according to WHO protocol. Blood pressure was measured by sphygmomanometer. Lipid profile was done by autoanalyser machine . Result : CCA PSV in Group A was found to be 57.67±13.33 and 48.55±16.29 in right and left side respectively & 70.06±14.04 and 75.23±11.89 in Group B . The data was highly significant (p<0.0001). CCA EDV in Group A was found to be 10.43±5.97 and 10.43±4.57 in right and left side respectively & 18.79±2.89 and 21.76±2.68 in Group B . The data was highly significant (p<0.0001). CCA RI in Group A was found to be 0.82±0.09 and 0.80±0.09 in right and left side respectively & 0.72±0.03 and 0.70±0.04 in Group B . The data was highly significant (p<0.0001).Age in Group A and B was found to be 62.93±5.82 and 52.59±4.37 respectively (p<0.0001). BMI in Group A and Group B was found to be 28.30±3.10 and 28.43±2.11 respectively (p =0.87).W/H in Group A and Group B was 0.88±0.03 and 0.89±0.02 respectively (p=0.22). Systolic and diastolic blood pressure in both the groups was found to be 150.75±13.48 & 139.18±6.63 and 87.50±5.72 & 84.09±5.60 which was statistically significant with p=0.001 & p=0.07. The difference between mean of two groups for HbA1c, HDL , LDL , total cholesterol and triglyceride in both the groups were 8.70±0.71 &7.25±1.08, 36.93±5.20 & 46.00±5.13, 146.81±7.96 &116.63±13.91, 229.62±6.87 & 194.95±15.48 &155.81±38.38, 169.36±29.85 respectively in which HbA1c, HDL, LDL,Total cholesterol were statistically very significant(p<0.0001) and triglyceride was not statistically significant. Conclusion: Our finding revealed that Common carotid artery hemodynamic parameters PSV, and RI were increased in stroke patients as well as EDV decreased in these patients. Smoking has association of development of stroke in hypertensive and diabetic patients. Carotid Doppler sonography is useful diagnostic modality for predicting and preventing CV Stroke in smokers as well as patients with hypertension and diabetes mellitus. [Makwana M Natl J Integr Res Med, 2019; 10(5): 7-10]