A Study of Clinical Profile of Acute Pancreatitis In AMC MET Medical College A Retrospective Study

Abstract

Background: Acute pancreatitis is a common disease with wide clinical variation and its incidence is increasing. Acute pancreatitis includes a wide spectrum of disease, from mild self limiting symptoms to a fulminant process with multiple organ failure and high mortality. Severity of acute pancreatitis is linked to the presence of systemic organ dysfunctions and/or necrotizing pancreatitis. Aim and objectives: The present study was aimed to study etiology and complications of acute pancreatitis, to assess the clinical profile of acute pancreatitis. Method: This was a hospital based cross sectional study was performed in AMCMET Medical college and Lg hospital Ahmadabad from January 2014- December 2015 to find out the clinical presentations of acute pancreatitis. All patients with a diagnosis of acute pancreatitis were included in this study with its clinical, laboratoty investigations and radiological data. Result: Of the 250 patients in this study, 150 were male (average age, 41 years) and 100 were female (average age, 32 years). Minimum age in my study is 12 years and maximum age is 70 years. Maximum number of patient is below 45 years of age that is 180 (72%) patient. In my study, 60 % male patient developed acute pancreatitis and   40 % of female. Alcohol identified as the most important etiologic factor associated with pancreatitis. Also incidence of alcohol association with acute pancreatitis was significantly increased in male, while gall stone pancreatitis was predominantly a disease of the female. Abdominal pain and vomiting were the most consistent symptoms in our study. Epigastric tenderness is present in 92% of cases. Guarding /rigidity are present in 52% of patient. 24% patient show jaundice as a sign of acute pancreatitis. CT grading system can identify patient at higher risk of mortality more accurately than clinical grading system; on other hand clinical grading system identify patient at risk of organ failure and requiring icu admission more accurately, so there is no major difference between both grading sysem. Conclusion: acute pancreatitis is one of the leading cause for increase morbidity and mortality to society.Cinical assessment along with lab markers correlated well with the mortality and morbidity.  Multiple organ failure, icu admission and mortality are higher in pancreatitis present with necrosis.