Impact of Tobacco Smoke on Tuberculosis: A Case Control Study

Impact of Smoking on Tuberculosis

Authors

  • Dr.Agarwal A
  • Dr.Agrawal V K

DOI:

https://doi.org/10.70284/njirm.v2i3.1918

Keywords:

India, Tuberculosis, Smoking

Abstract

Abstracts: Background:, Smoking increase the risk of tuberculosis 2-4 times , In our country half of tubercular death in men is attributed to smoking, around 17% smokers and 1/3 tubercular patients of the world reside here . Objective: To study the impact of smoking on sputum status and clinico radiological profile of tubercular patients. Method: We did a case control study , comprises in two groups , study and control group , a total of 120 Tubercular (Pulmonary & Extra-pulmonary) patients were studied in which 65 were smoker( study group) , 55 non smoker ( control group),. Detailed clinico-radiological study was done during the period of 9 months. Result: The prevalence of tuberculosis ( Pulmonary & extra pulmonary ) among smokers is 23.63%, out of them prevalence of pulmonary tuberculosis 80% ( odd ratio OR 4.8) , cough ( 98.4%), and Dyspnoea( 93.8%) was prominent clinical symptoms in study group, as well as cavitations ( 98.07%), & fibrosis ( 98.07%) radio logically significant presentation in smokers besides this relapse as well as re infection was higher among smoker’s (64.61%).Sputum positivity was high for heavy smokers (86.7%) . Extra-pulmonary tuberculosis low (20%) in study group (0.21). Conclusion: Smoking is a significant risk factor for pulmonary tuberculosis as well as it aggravates the severity and relapse of diseases.

References

1. Gupta K.B. ,Gupta R.. Association between smoking and tuberculosis, Ind.J.Tub.200350:5-7.
2. ReddyK.S., GuptaP.C.,editors, Prevalence of tobacco use. Report on Tobaccocontrol in India.New Delhi: Ministry of Health and Family Welfare, Govt. of India2004:pp 49-56.
3. John R. Tobacco consumption pattern and its health implication in India , Health policy 2005; 71: 213-22.
4. Gajalakshmi V., Peto R., Kanaka S.T., Jha P. Smoking and mortality from tuberculosisand other diseases in India: Retrospective study of 43,000 adult male deaths and 35,000 controls.Lancet 2003:362;507-15.
5. Shprykov AS, Zhadnov VZ. Effect of tobacco smoking on the course of infiltrative pulmonary tuberculosis and effectiveness of its treatment . Probl Tuberk 1994;(5):26.
6. Kolappan C., Gopi P.G. Tobacco smoking and pulmonary tuberculosis; Thorax 2002; 57: (11) , 964-966.
7. Fernandez MA.I Alonso Mallo E., Labato Delgado LA , Martivez Sanchcz JM. Extra-Pulmonary Tuberculosis : Retrospective study of 107 cases. Am Med.Interna.1995 ;12(5) : 212.
8. Prasad R., Garg R., Singhal S. , Dawar R., Agrawal G.G. A case control study of tobacco smoking and tuberculosis in India; Annals of Thoracic Medicine, vol.4;issu 4;208-210.
9. Linn H.H., Ezzati M., Chang H.Y., Murray M. Association between tobacco smoking and active tuberculosis in Taiwan: Prospective Cohort study; Am J Respir Crit Med 2010 Feb 1 ; 181(3): 290-1.
10. Kolappan C., Gopi P.G. Tobacco smoking and pulmonary tuberculosis; Thorax 2002; 57: (11) , 964-966.
11. Leung C.C., Lam TH, Ho K.S. ,Yew W.W., Tam C.M., Chan W.M., et al. Passive smoking and tuberculosis; Arch Intern Med. 2010 Feb 8 ; 170 ( 3): 292-3.
12. Dheda K., Margeret A.J., Zumla A., Graham A.R. Smoking is not beneficial for tuberculosis; Am J Respir Crit Med 2004;170;821 .
13. Jindal S.K., Agrawal A.N., Chaudhry K., Chhabra S.K., Gupta D., Katiyar S.K. Tobacco Smoking in India : Prevalence , Quit rates and Respiratory Morbidity; Ind.J.Chest Dis. Allied Sci. 2006;48: 37 42.
14. Karen S., Chiang C.Y., Donald A.E. Tobacco cessation interventions for tuberculosis patients- A guide for low income countries; IUATLD 2008; 4
15. Racil H., Amar J.B., Cheikrouhou S., Hassine E.,Zarrouk M., Chaouch N. et al. Pulmonary tuberculosis in smokers; Presse Med. 2010 Feb;39(2): 159-60
16. Fortun J. , Sierra C., Raboso E. Pcrez C., Pluza G., Navas et al. Tuberculosis of the otorhinolaryngologic region ; Laryngeal and Extra-Laryngeal forms. Enferm Infec. Microbiol.clim 1996: 14(6):352

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Published

2011-09-30

How to Cite

A, D., & V K, D. (2011). Impact of Tobacco Smoke on Tuberculosis: A Case Control Study: Impact of Smoking on Tuberculosis. National Journal of Integrated Research in Medicine, 2(3), 38–42. https://doi.org/10.70284/njirm.v2i3.1918

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