Saliva as a Diagnostic Aid in Periodontitis -A Biochemical Study
Saliva as a Diagnostic Aid in Periodontitis -A Biochemical Study
DOI:
https://doi.org/10.70284/njirm.v8i2.1215Keywords:
Saliva, diagnostic aid, alkaline phosphatase, aspartate aminotransferaseAbstract
Aim: To study the saliva as a diagnostic aid in gingivitis and periodontitis patients. Method: The study includes 60 subjects of both sexes aged between 15-55 years. 60 subjects were divided into 3 groups of 20 individuals each. Further, each group was divided equally into 10 males and 10 females. The three groups were: (1) Healthy patients who have no gingival or periodontal disease, (2) Gingivitis patients in whom the findings are confined only to gingiva and (3) Third group included periodontitis patients who have periodontal pockets ≥ 4 mm as well as clinical attachment loss. Unstimulated whole saliva samples were been collected and it was transported to the laboratory for biochemical analysis of alkaline phosphatase enzyme, aspartate aminotransferase enzyme and calcium ions, within 24 hours. Result: Results showed, the level of alkaline phosphatase enzyme, aspartate aminotransferase enzyme and calcium ions was found significantly higher in the periodontitis group as compared to the gingivitis and healthy groups. Conclusion: Saliva can be used as an aid in the diagnosis of periodontal disease by identifying the biochemical markers. More longitudinal studies examining the relationship of these identified biochemical markers to the natural history of periodontal disease is the obvious next step in the line of investigation. [Jaladh P NJIRM 2017; 8(2) :106-109]
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