Antibiotic Susceptibility Pattern of Uropathogens in Pediatrics Patients
Antibiotic Suceptibility Pattern Of Uropathogens In Paediatrics Patients
DOI:
https://doi.org/10.70284/njirm.v8i2.1201Keywords:
Children, urinary tract infection, uropathogensAbstract
Background & Objectives: To identify the pathogens and their antibiotic susceptibility patterns in UTI cases in Paediatric patients.To help in implementation of better therapeutic strategies to reduce morbidity and mortality in Paediatric patients. Methods: Urinary isolates were analyzed retrospectively, data was collected and analysed. Isolation and identification of pathogens was done by standard microbiological method and antibiotic susceptibility test was done using modified Kirby-Bauer disk diffusion method according to current Clinical and Laboratory Standard Institute (CLSI) guidelines. Results: Out of total 1001 urine samples uropathogens were isolated from 334(33.4%) samples. The pathogensisolated were:219/334(65.6%) Enterobacteriacae, 52/334(15.6%) Nonfermenters, 41/334(12.3%) Candida spp, 22/334 (6.5%) GPC (Gram positive cocci).In the Enterobacteriacae group most common pathogen isolated wasE. colifollowed byKlebseilla spp. Most of these isolates were resistant to commonly used antibiotics like 2nd and 3rd generation cephalosporins, fluoroquinolones and were sensitive to carbapenams, nitrofurantoin and newer fluoroquinolones like levofloxacin. Among the nonfermenters,Pseudomonas were resistant to 3rd generation cephalosporins and sensitive to imipenam and polymyxin B. Conclusion: In the spectrum of paediatric UTI, Enterobacteriacaeare the most common etiology and they exhibit high degree of drug resistance to commonly used antibiotics. Suitable antibiotic policy can help in minimising drug resistance. [Padaria N NJIRM 2017; 8(2):51-54]
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