Role of Complete Blood Count and C – Reactive Protein as Diagnostic Markers in Sepsis In Neonatal Intensive Care Unit Patients
Role of complete blood count and C – reactive protein as diagnostic markers
DOI:
https://doi.org/10.70284/njirm.v8i2.1186Keywords:
CBC, HS CRP, NICUAbstract
Background: Neonatal Intensive care unit is complex components of health care. Severe sepsis mortality ranges from 28% to 50%. Markers of inflammation, as C- reactive protein, erythrocyte sedimentation rate and complete blood counts are still useful investigations for sepsis in NICU. Research Objective: To access and analyse correlation between CBC and CRP concentration among NICU patients and to NICU outcome and its relationship with the diagnosis. Methodology: This cross-sectional study was carried on 327 patients admitted in NICU at C. U. Shah medical college and hospital. From time of admission to discharge day, signs and symptoms, clinical and laboratory data regarding CBC and CRP levels collected with other relevant tests according to the patient's clinical status. Results: In 92.92 % of all NICU patients with sepsis, CRP was >30 mg/L. Of all NICU patients with sepsis, leucocytosis, thrombocytopenia and raised absolute neutrophil count was observed in 66.13%, 13.53% and 56.8% respectively. Conclusion: Leukocytosis and neutrophilia are predictive of sepsis. CRP value greater than 30.0 mg/L is 90 percent sensitive and sequential assessment of CRP values is specific for diagnosis of sepsis. If the CRP level remains persistently normal, bacterial sepsis is unlikely.[Shivani TNJIRM 2017; 8(2):1-4]
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