Cytomorphological Patterns of Benign Breast Lesions In A Tertiary Care Hospital
Cytomorphological Patterns of Benign Breast Lesions In A Tertiary Care Hospital
DOI:
https://doi.org/10.70284/njirm.v9i4.2378Keywords:
Breast, FNAC, fibroadenomaAbstract
Introduction: Benign breast lesions refer to a variety of diseases that may present a wide range of clinical signs and symptoms. Most of the palpable breast lumps are benign but still cause a significant anxiety to the patient and also to the family members. Some of the benign breast lesions are known to be a predisposing risk factor for developing malignancy in later part of the life if not treated in time. Therefore it is mandatory to identify these lesions for appropriate management. Methods: The present study was a retrospective study carried in department of pathology of a tertiary care hospital between April 2016 and March 2018 and included 307 patients who presented with palpable breast lumps. Cytomorphological features of benign breast lesions were studied. The findings were tabulated and analyzed. Results: There were 288 female and 19 male patients. The most common age group involved was 21-30 years. Most of the lumps were of size ≤ 2 centimeters (cms). Maximum number of lesions encountered in our study on FNAC were fibroadenoma followed by benign proliferative mammary lesion. Conclusion: FNAC is a safe, cost effective and outpatient procedure. FNAC gives result very fast and is accurate therefore it is very useful in benign breast lesions to avoid fear of surgery and also gives psychological relief to the patient. [M Chaudhry, Natl J Integr Res Med, 2018; 9(4):32-36]
References
Ramanujam R. Benign breast diseases: experience
at a teaching hospital in rural India. Int J Res Med
Sci. 2013;1(2):73.
2. Guray M, Sahin AA. Benign breast
diseases:classification, diagnosis, and
management.The Oncologist. 2006;11(5):435-449.
3. Vaidyanathan L, Barnard K, Elnicki DM. Benign
breast disease: When to treat, when to reassure,
when to refer. Cleve Clin J Med. 2002;69:425-32.
4. Vimal M, Chitra T. Spectrum of benign breast
diseases in females of reproductive age group.
Journal of Research in Medical and Dental Science.
2016;4(2):137-40.
5. Chaiwun B, Settakorn J, Ya-In C, Wisedmongkol W,
Rangdaeng S, Thorner P. Effectiveness of fineneedle
aspiration cytology of breast: Analysis of 2375 cases from northern Thailand. Diagn
Cytopathol. 2002;26:201-5.
6. Nguansangiam S, Jesdapatarakul S, Tangjitgamol
S. Accuracy of fine needle aspiration cytology from
breast masses in Thailand. Asian Pac J Cancer
Prev. 2009;10:623-6.
7. Cobb CJ, Raza AS. Obituary: ―Alas poor FNA of
breast — We knew thee well!. Diagn Cytopathol.
2005;32:1-4.
8. Kaufman Z, Shpitz B, Shapiro M, Runa R, Lew S,
Dinbar A. Tripple approach in the diagnosis of
dominant breast masses: Combined physical
examination, mammography and fine needle
aspiration. J Surg Oncol. 1994;56:254-7.
9. Rosai J. The breast. Rosai and Ackerman’s Surgical
Pathology. 9th ed. Vol 2. St. Louis, Missouri.
Mosby; 2004:pp.1763-1876.
10. Farkhanda JD, Muhammad SA, Ahsan AL, Noor
MK, Imtiaz S, Zulfiqar IM. An early diagnosis of
benign breast diseases. Journal of Surgery
Pakistan. 2010;15(4):74-78.
11. Godwins E, David D, Akeem J. Histopathologic
analysis of benign breast diseases in Makurdi,
North Central Nigeria. International Journal of
Medicine and Medical Sciences. 2011;3(5):125-
128.
12. Naveen N, Mukherjee A, Mahajan V. A clinical
study of benign breast disease in rural population.
J Evol Med Dent Sci. 2013;2(30):5499–511.
13. Karki OB, Kunwar D, De A. Benign Breast Diseases:
Profile at a Teaching Hospital. Am J Public Health
Res. 2015;3(4A):83–6.
14. Guray M, Sahin AA. Benign breast diseases:
classification, diagnosis, and management. The
Oncologist. 2006;11(5):435–49.
15. Dahri FJ, Awan MS, Leghari AA, Khaskheli NM,
Soomro I, Memon ZI. An early diagnosis of benign
breast diseases. J Surg Pak Int. 2010;15(4):186.
16. Muddegowda PH, Lingegowda JB, Kurpad R, PG
Konapur, AS Shivarudrappa and PM Subramaniam.
The value of systematic pattern analysis in FNAC
of breast lesions: 225 cases with cytohistological
correlation. J Cytol. 2011;28(1):13-19.
17. Chandanwale S,Rajpal M, Jadhav P, Sood S, Gupta
K, Gupta N. Pattern of benign breast lesions on
fnac in consecutive 100 cases: a study at tertiary
care hospital in India. IJPBS. 2013;4:129-138
18. Krishnaswamy U. Profile of benign breast diseases
in urban India. Indian J Surg. 2003; 65(2):178-181.
19. Malik R, Bhardwaj VK; Breast lesions in young
females. A 20 year study for significance of early
recognition. Indian J Pathol Microbiol. 2003;46(4):
559-562.
20. Jyoti Priyadarshini Shrivastava, Alok Shrivastava.
“Fine Needle Aspiration Cytology of Breast Lumps
with Clinical and Histopathological Correlation: A 2
Year Study in Gwalior, Indiaâ€. Journal of Evolution
of Medical and Dental Sciences. 2015;4: 9729-
9734.
21. Carter BA, Page DL, Schuyler P, Parl FF, Simpson
JF, Jensen RA, et al. No elevation in long-term
breast carcinoma risk for women with
fibroadenomas that contain atypical hyperplasia.
Cancer. 2001;92(1):30–6.
22. Chandanwale SS, Gupta K, Dharwadkar AA, Pal S,
Buch AC, Mishra N. Pattern of palpable breast
lesions on fine needle aspiration: A retrospective
analysis of 902 cases. J Midlife Health.
2014;5(4):186–191.
23. Coen P, Kulin H, Ballantine T, Zaino R,
Frauenhoffer E, Boal D, et al. An aromatase
producing sex-cord tumour resulting in
prepubertal gynaecomastia. N Engl J Med.
1991;324:317–22.
24. Hamperal H. The myoepithelia (myoepithelial
cells): Normal state; regressive changes;
hyperplasia; tumors. Curr Top Pathol.
1970;53:161-220.
25. Apocrine adenoma of breast.
PathologyOutlines.com website.
http://www.pathologyoutlines.com/topic/breasta
pocrineadenoma.html. Accessed May 30th, 2018.
26. Michie C, Lockie F, Lynn W. The challenge of
mastitis. Arch Dis Child. 2003 ;88(9):818–21.
27. Pagel W, Simmonds F, Mcdonald J, Nassan E.
Pulmonary tuberculosis. 4th ed. London. Oxford
University Press;1964:pp.900.
28. Mehrotra R. Fine Needle Aspiration Diagnosis of
Tuberculous Mastitis. Indian J. Pathol Microbiol. 2004; 47(3): 377-380.
