Serum Homocysteine In Acute Ischaemic Cerebrovascular Stroke

Abstract

Background: There is evidence that high serum homocysteine is a poor prognostic factor in patients with acute
ischaemic cerebrovascular stroke. Our study showed a close correlation of serum homocysteine and National
Institutes Of Health Stroke Scale Score (NIHSS score) in patients of acute ischaemic cerebrovascular stroke.
Material and Methods: 50 indoor cases of acute ischemic cerebrovascular accidents were studied. All patients
underwent serum homocysteine determination and the NIHSS score of all the patients at admission were
calculated.
Results: Most patients with a better prognosis as determined by their lower NIHSS score had a lower serum
homocysteine level, and most with a worse prognosis as per their higher NIHSS score and a higher serum
homocysteine level.
Conclusion: Higher level of serum homocysteine is associated with a poorer short term prognosis. Thus, it may
act as an indicator of short term prognosis in acute ischaemic cerebrovascular stroke.