Primary metaplastic squamous cell carcinoma of breast

Abstract

38 years old female patient presented with a lump in left breast since 6 months, gradually progressive in size, ultimately involving almost entire breast. She also had a lump in left axilla. She had no complaint of pain over the lump or skin changes. There was no history suggestive of distant metastasis. Trucut biopsy from left breast lump showed poorly differentiated carcinoma with squamoid differention. In whole body PET CT scan, there was no distant metastasis. Patient underwent left sided modified radical mastectomy. Histopathological examination diagonosed the case as metaplastic squamous cell carcinoma. In immunohistochemistry, it was triple negative breast carcinoma. Patient received adjuvant chemotherapy and radiotherapy. The case is described along with a review of literature.