Arsenic induced squamous cell carcinoma of skin – atypical presentation with aggressiveness.

Abstract

junction of neck and thorax (left side) and a lump at left upper neck. On examination, ulcer was 3×3 cm. In size. There was an enlarged lymph node at level I I cervical region. There were hyperkeratoses and hyperpigmentation at multiple site. Patient had lost one finger at left upper extremity. Biopsy and histopathological examination from the ulcer revealed squamous cell carcinoma. CT scan of whole abdomen showed multiple hypodence space occupying lesion in liver, consistent with metastasis. Patient was treated with chemotherapy with palliative intent. This case has atypical presentation with aggressiveness in behaviour. The case is described along with a review of literature.