Keratoacanthoma of the oral cavity with osteomyelitis of the mandible

Abstract

Introduction- Keratoacanthoma is a benign proliferative disease of the epithelium. It is commonly seen in the exposed parts on the lips, cheek nose and dorsum of the hand. It is rarely seen in the oral cavity. Keratoacanthoma of the oral cavity with mandibular osteomyelitis has not been reported until now. Case report- We report a case of keratoacanthoma of the oral cavity with mandibular osteomyelitis. 82 years old patient with oral lesion of 5 months duration with history of tooth extraction, biopsy was nonconfirmative for malignancy and the CT scan showed destructed mandible. He underwent excision and reconstruction with mandibular reconstruction plate and advancement flap. Histo pathology was reported askeratoacanthoma of the oral mucosa and osteomyelitis of the mandible. Conclusion- Keratoacanthoma may be a differential diagnosis for well differentiated squamous cell carcinoma. Tooth extraction could be the aetiology for keratoacanthoma and the osteomyelitis of the mandible.