Case series of necrotizing fasciitis due to Candida tropicalis and review of fungal necrotizing fasciitis from India

Abstract

Necrotizing fasciitis (NF) comprise a spectrum of disease entities that are characterized by extensive, rapidly progressive soft-tissue necrosis and is associated with a high mortality. Here we report a case series of 3 patients diagnosed as mono microbial NF. All the isolates were Candida tropicalis and all were sensitive to amphotericin B, voriconazole and caspofungin and resistant to fluconazole. They all were isolated from the tissue sample as per standard mycological techniques. Despite timely diagnosis and treatment with amphotericin B one patient died.